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Blood clot bandages may speed gum surgery recovery

NCT ID NCT07439068

Symptom relief Sponsor: Ordu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether applying advanced platelet-rich fibrin (A-PRF) or concentrated growth factor (CGF) membranes to the roof of the mouth after a gum graft could reduce pain and speed healing. Forty-five adults who needed a gum graft were randomly assigned to receive one of these treatments or a standard gelatin sponge. The researchers measured how quickly the wound closed and how much pain people felt over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF) membranes
What this could lead to
If it works, this could lead to faster, less painful healing after gum graft surgery.
What could go wrong
This is a small, early-phase trial with only 45 participants, so results may not apply to everyone. The treatments are procedures, not drugs, and their benefit over standard care is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

45 people

The number who actually took part.

Started

Nov 2020

Finished

May 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * at least 18 years old, * without systemic or periodontal diseases, * without medical contraindications to periodontal surgery * with full-mouth plaque control scores ≤ 20% * Gingival index scores ≤ 1 Exclusion Criteria: * smoking habits, * diabetes mellitus, * pregnancy or lactation, * removable upper denture, * regular medication that could interpose the healing process, undergoing bisphosphonate therapy, history of radiation therapy of the jaws, and follow-up consults

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Free gingival graft

Contacts and locations

Locations

  • Ordu University

    Ordu, 52100, Turkey (Türkiye)

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