Zhejiang Cancer Hospital

This study tests a powerful two-step approach for people with a fast-growing type of lymphoma that has not responded to standard treatments. First, patients receive a CAR-T cell therapy (engineered immune cells) followed by a stem cell transplant with high-dose chemotherapy. The …

This Phase 3 trial tests whether a sequence of chemotherapy drugs (AG followed by mFOLFOX) plus two immunotherapy agents (serplulimab and bevacizumab) works better than standard AG chemotherapy alone for people with advanced pancreatic cancer that cannot be removed by surgery. Ab…

This phase 2 trial is testing a new approach for adults with early-stage (I-II) MALT lymphoma, a slow-growing cancer. Participants first receive a very low dose of radiation (4 Gy total) over two days, then take a daily targeted drug called orelabrutinib for up to 6 months. The g…

This study tests a new way to give chemotherapy for breast cancer that has spread to the liver and stopped responding to standard treatments. The drugs are delivered directly into the liver artery to target tumors while reducing side effects. About 30 adults aged 18-70 with liver…

This study tests a new drug called distamab vedotin (RC48) combined with carboplatin for people with advanced ovarian cancer that has a specific protein called HER2. The goal is to see if this combination works better and causes fewer side effects than standard chemotherapy. Abou…

This study looks at what happens when people with HER2-positive advanced breast cancer switch between two different targeted therapy combinations after their first treatment stops working. About 600 women will be split into two groups: one switches from HP+chemo to HPy+chemo, the…

This study tests whether adding two drugs (entinostat and anlotinib) to a standard hormone therapy (fulvestrant) can shrink tumors or slow cancer growth in people with a common type of advanced breast cancer (HR+/HER2-). About 118 adults whose cancer returned or worsened after pr…

This study tests whether a single infusion of umbilical cord blood can safely raise platelet levels in cancer patients whose platelets have dropped due to chemotherapy or other cancer treatments. Researchers will enroll 25 people aged 12 to 65 and monitor their blood counts for 2…

This study tests whether adding the experimental drug IBI363 to standard chemotherapy can better shrink or eliminate stomach or gastroesophageal junction cancer before surgery. It includes 60 adults aged 18-75 whose tumors lack a certain immune marker (MHC-II negative). The main …

This study tests a combination of three drugs (thiotepa, pirtobrutinib, and sintilimab) for people with a type of brain lymphoma that has come back or is hard to treat. The goal is to see if this mix can shrink tumors and help patients live longer. About 24 adults will take part,…

This study tests an injectable imaging agent called NC527-X that makes tumors glow during surgery, helping surgeons see and remove them more precisely. About 400 adults with solid tumors who are scheduled for surgery will receive the injection before their operation. The main goa…

This study looks at how taking American ginseng for two weeks changes the chemicals in urine and blood of healthy adults. Twenty people aged 18 to 45 will take 3 grams of ginseng powder daily. Researchers will use advanced lab tests to track metabolic changes and monitor for any …

This study will review medical records of 200 patients in China with HER2-negative metastatic breast cancer who received sacituzumab govitecan. Researchers want to see how long the drug keeps cancer from growing and how well patients tolerate it. The goal is to understand real-wo…

This study uses CT scans to see how three different breathing tubes (laryngeal masks) sit in the throat of patients under general anesthesia. Researchers want to understand which device fits best and causes the least tissue pressure. Nine adults scheduled for CT-guided procedures…

This study watches how normal throat structures move during a barium swallow test in people already having a routine barium meal exam. The goal is to learn more about these movements to help design better laryngeal masks, which are devices used to help patients breathe during med…