Wake Forest University Health Sciences

This study aimed to see if adding a special electromagnetic field treatment to the cancer drug regorafenib could better control advanced liver cancer that had worsened after initial therapy. It was for patients whose cancer had progressed despite standard first-line treatments. T…

This early-stage trial tested the safety of combining two chemotherapy drugs (gemcitabine and docetaxel) with radiation before surgery for adults with large, aggressive soft tissue sarcomas in the arms or legs. The main goal was to find the highest dose patients could tolerate wi…

This early-stage study tested whether combining a precise form of radiation (radiosurgery) with an immunotherapy drug (pembrolizumab) was safe and feasible for people with cancer that had spread to the spine. The main goal was to see if patients could complete both treatments. Re…

This study aimed to compare two brands of surgical mesh used to repair a common type of abdominal hernia. It looked at how often the hernia came back and if there were complications with each mesh. The trial was very small and was stopped early, so no clear results are available.

This study aimed to see if a spinal cord stimulator could help reduce pain in people with painful diabetic neuropathy. The device sends electrical pulses to the spinal cord to interfere with pain signals. The study was terminated early after enrolling only 6 participants, so resu…

This study tested an online support group designed to help young adults who have finished cancer treatment cope with anxiety and depression during the COVID-19 pandemic. Researchers wanted to see if teaching healthy coping skills through virtual meetings could improve participant…

This study aimed to see if a therapy called blood flow restriction (BFR) could help people recover faster from a recent shoulder injury. BFR involves wearing a special pressurized cuff on the arm during light rehab exercises to try and prevent muscle loss. The trial was very smal…

This study tested whether a temporary nerve stimulation device could help people with chronic knee pain from osteoarthritis. The device was meant to block pain signals from the knee. Researchers measured changes in pain levels, quality of life, and medication use in a small group…

This study tested whether a drug called solriamfetol, which promotes wakefulness, could help adults with stable brain tumors (gliomas) feel less sleepy and fatigued, and improve their memory and quality of life. The main goal was to check the drug's safety at different doses. The…

This early research study tested whether giving the antifungal drug ketoconazole for a few days before brain tumor surgery could affect tumor biology. The study involved 15 patients with either recurrent brain tumors (gliomas) or breast cancer that had spread to the brain. Resear…

This study aims to collect detailed information about how blood flows to the brain in critically ill patients who need a temporary mechanical heart pump. Researchers will use a non-invasive ultrasound test on the head to measure brain blood flow and see how it relates to the sett…

This small, ended pilot study tested if a wearable blood sugar monitor (CGM) could be used for patients with diabetes before, during, and after surgery. It aimed to see if the monitors were practical to use in the hospital and if their readings were accurate compared to standard …

This study aimed to understand if the hormone oxytocin, given through an IV, could reduce pain. Researchers tested this by applying a mild, heated probe to the skin of healthy volunteers and people with severe knee arthritis, asking them to rate their pain. The goal was to create…

This small pilot study tested a new support program called SHAREDCare for people who have finished treatment for lung cancer. The goal was to see if working with a care navigator to create a personalized plan could help survivors better manage their ongoing health and social need…