Vanda Pharmaceuticals

This study tests whether the drug iloperidone can lower blood pressure in people whose hypertension remains uncontrolled despite taking one or more standard medications. About 240 adults with systolic blood pressure of 130 mmHg or higher will receive either iloperidone or a place…

This early-stage study tests the safety of a drug called trichostatin A in adults with blood cancers that have returned or not responded to standard treatments. About 42 participants will receive the drug to find the highest safe dose and identify side effects. The goal is not a …

This study tests whether adding milsaperidone to current antidepressant treatment helps reduce depression symptoms in adults whose current medication isn't working well enough. About 500 people with major depressive disorder will receive either milsaperidone or a placebo (inactiv…

This study tests a single-dose pill called VQW-765 to see if it can quickly reduce acute anxiety during social situations in adults with social anxiety disorder. About 500 participants will receive either the drug or a placebo, and their distress levels will be measured during a …

This study tests whether a daily medication called tasimelteon can help people with Delayed Sleep-Wake Phase Disorder (DSWPD) fall asleep earlier and sleep better. About 70 adults with DSWPD will take either the drug or a placebo for several weeks. The main goal is to see if the …

This study tests whether a new eye drop called VSJ-110 can safely relieve dry eye symptoms. About 160 adults with dry eye will receive either the active drop or a placebo for eight weeks. Researchers will check eye surface health, tear production, and patient-reported discomfort.

This study tests whether tradipitant can reduce nausea and vomiting caused by GLP-1 weight-loss medications. About 280 healthy overweight or obese adults will receive either tradipitant or a placebo. The goal is to help people stay on their weight-loss treatment without unpleasan…