University Of Ulm

This study looks at a treatment called immunoadsorption (IA) for people with chronic inflammatory demyelinating polyneuropathy (CIDP), a nerve disease that causes weakness and numbness. About 140 adults who did not get better with standard treatments will be switched to IA and fo…

This study compares two blood-filtering treatments—immunoadsorption and plasma exchange—for people with Guillain-Barré syndrome (GBS), a rare nerve disorder that can cause muscle weakness and paralysis. Researchers will enroll 20 adults to see which treatment is safer and more ef…

This study tests whether adding venetoclax to standard chemotherapy helps adults with newly diagnosed acute myeloid leukemia (AML) or related conditions live longer without the cancer returning. About 650 participants aged 18 to 75 will receive either venetoclax or a placebo alon…

This study tests if a blood-filtering method (immunoadsorption) works better than standard antibody infusions (immunoglobulins) for people with chronic inflammatory demyelinating polyneuropathy (CIDP) who did not improve with steroids. About 20 adults with CIDP for 3 years or les…

This study tests whether a high-calorie diet given through a feeding tube can slow the progression of ALS, a disease that weakens muscles. Researchers will compare a diet with 20% more calories than needed to a standard-calorie diet in 76 people with ALS who already use a feeding…

This study tests whether a very high-calorie, fatty diet can help people with ALS live longer and slow the disease. About 392 participants with early-stage ALS will either follow the special diet or a placebo. The main goal is to see if the diet improves survival and daily functi…

This study is a registry that collects health information from people with lipodystrophy, a rare condition where the body loses or does not grow fat tissue properly. Researchers will follow up to 5,000 participants over many years to track disease progression, complications, and …

This study looks at how blood sugar levels change in healthy soldiers during a 6 km march while carrying 15 kg of equipment. Researchers will measure glucose, heart rate, and stress hormones before and after the march. The goal is to understand what factors influence blood sugar …

This study looks at how gestational diabetes (diabetes during pregnancy) might change the baby's genetic instructions. Researchers will collect blood from the mother, father, and use cell-free DNA from the mother's blood to study the baby's epigenetics. The goal is to understand …

This study uses advanced brain scans (MRI) to look for differences in brain structure, function, and chemistry between people with metabolic diseases and healthy volunteers. Researchers will track these changes over time and see how they relate to body fat and weight. The goal is…

This study creates a global registry to collect information from people with genetic obesity, a rare condition caused by gene changes that affect appetite and metabolism. Researchers aim to gather data from up to 5,000 participants to better understand how the condition progresse…

This study is a large registry that will follow up to 50,000 adults with acute myeloid leukemia (AML) or related blood cancers for up to 10 years. Researchers will collect medical history, genetic markers, and treatment outcomes to better understand the disease and improve future…

This study looks at how changing thyroid hormone levels impact the way the body uses sugar and fat. Researchers will measure insulin sensitivity and energy use in 60 people with Graves' disease or thyroid cancer before and after their hormone levels are adjusted. The goal is to b…