University Of Ulm

This Phase 3 trial is testing whether adding the drug venetoclax to standard chemotherapy helps adults with newly diagnosed acute myeloid leukemia (AML) or a related condition live longer without the cancer coming back. About 650 people aged 18 to 75 will be randomly assigned to …

This study tests whether giving ALS patients 20% more calories than their body needs (via a feeding tube) can slow the disease. Researchers will measure a nerve damage marker in the blood over 6 months. 76 adults with ALS who already use a feeding tube will be randomly assigned t…

This study tests whether an ultra-high-caloric, fatty diet (100% fat, no protein or carbs) can improve survival and slow disease progression in people with ALS. Researchers will compare the diet to a low-fat placebo in 392 participants. The main goal is to see if the diet extends…

This study looks at whether a blood-filtering procedure called immunoadsorption can help people with chronic inflammatory demyelinating polyneuropathy (CIDP) who do not get better with standard treatments like intravenous immunoglobulins or steroids. About 140 adults with CIDP wi…

This study compares two blood-filtering treatments—immunoadsorption and plasma exchange—for people with Guillain-Barré syndrome (GBS), a rare nerve disorder that can cause muscle weakness and paralysis. Researchers will enroll 20 adults to see which method is safer and more effec…

This study compares two treatments for CIDP, a nerve condition that causes weakness and numbness. It involves 20 adults who did not get better with steroids. One group receives a blood-filtering procedure called immunoadsorption, and the other receives standard antibody infusions…

This study looks at how the metabolism of both parents during pregnancy may change the baby's epigenetics—chemical marks on DNA—in gestational diabetes. Researchers will test 80 pregnant women and their partners, analyzing blood and fetal cell-free DNA. The goal is to better unde…

This study is a European registry for people with lipodystrophy, a rare condition where the body loses or lacks fat tissue. Researchers will follow up to 5,000 patients over time, collecting health data and genetic information. The goal is to better understand the disease, its pr…

This study tracks blood sugar levels in 100 healthy soldiers as they complete a 6-kilometer march carrying 15 kilograms of gear. Researchers will use continuous glucose monitors and heart rate sensors to see how exercise affects glucose and the nervous system. The goal is to bett…

This study looks at how changing thyroid hormone levels affect the way the body uses sugar and fat. Researchers will study people with Graves' disease (whose thyroid hormones are too high) and people with thyroid cancer (whose hormones are intentionally raised). Participants will…

This study creates a global database to collect information from people with genetic obesity. Researchers aim to learn how the condition progresses, what complications arise, and how different genetic types respond to standard treatments. Up to 5,000 participants will share data …

This study is a registry that collects information from up to 50,000 adults with acute myeloid leukemia (AML) or related blood cancers. Researchers will track patients' genetics, treatment responses, and long-term outcomes over up to 10 years. The goal is to better understand the…

This study uses brain MRI scans to look for differences in brain structure, function, and chemistry between people with metabolic diseases (like obesity or diabetes) and healthy volunteers. Researchers will also measure body fat using MRI. The goal is to understand how metabolism…