Could extra calories slow ALS? new trial tests feeding tube nutrition

NCT ID NCT06877143

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether giving ALS patients 20% more calories than their body needs (via a feeding tube) can slow the disease. Researchers will measure a nerve damage marker in the blood over 6 months. 76 adults with ALS who already use a feeding tube will be randomly assigned to get either their exact calorie needs or 20% extra.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
hypercaloric PEG nutrition (120% of calorie needs)
What this could lead to
If it works, this could point toward a simple dietary strategy to slow ALS progression and improve survival.
What could go wrong
This is a small, early-phase trial (76 people) and the benefit is uncertain. The intervention is only for patients already using a feeding tube, so results may not apply to all ALS patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ulm Universita, Department of Neurology

    RECRUITING

    Ulm, Baden-Wurttemberg, 89081, Germany

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