University Of Sydney

After a kidney or kidney-pancreas transplant, the body may attack the new organ—a problem called acute T cell mediated rejection. Doctors use strong steroids to treat it, but there's no standard dose, and too much can cause serious side effects. This phase 3 trial with 540 partic…

This study tests a new way to plan radiation therapy for people with stage 3 lung cancer. The method uses CT ventilation imaging to identify and avoid the healthiest parts of the lungs during treatment. Researchers want to see if this approach helps patients maintain a better qua…

This study tests three home-based programs for people with long-term muscle or joint pain (like back pain or arthritis) who also sleep poorly. Participants will be randomly assigned to exercise, cognitive behavioral therapy for insomnia, or both, with up to 10 online sessions ove…

This study is testing whether special MRI scans can identify low-oxygen (hypoxic) areas in glioblastoma, an aggressive brain cancer. Researchers will compare these scans with a standard PET imaging method in 20 participants. The goal is to see if MRI can reliably guide radiation …

This study tests whether special X-ray imaging techniques can show which parts of the lung are working best. The goal is to help doctors plan radiation therapy that avoids these healthy areas. Fifteen adults with stage II-IV lung cancer will receive extra scans before and after t…

This study is developing an artificial intelligence system that can track the movement of tumors and nearby organs during radiation therapy without needing implanted markers. Researchers will use data from 300 patients receiving radiation for various cancers or heart arrhythmias …

This study tests a new type of CT scan (Real-Time Gated 4DCT) for people with lung cancer who are scheduled for radiation therapy. The goal is to see if this scan can produce clearer images with fewer blurry spots (artifacts) compared to the standard scan. About 30 adults will ge…

This study tests whether a new technology called Markerless Tumour Tracking can accurately guide lung cancer radiotherapy without the need for implanted markers. About 30 people with early-stage lung cancer or limited lung metastases will participate. The goal is to see if the ne…