University Of Oxford

This study tests a new malaria vaccine in healthy adults (18-35 years) and children (5-17 months) in Burkina Faso. The vaccine combines three components to target different stages of the malaria parasite. The main goal is to check safety and how well the body's immune system resp…

This study tests whether a quick, dye-free MRI scan can find liver cancer earlier than the standard ultrasound in 300 people with cirrhosis who are at high risk. Participants will get both scans every 6 months for 2.5 years. The goal is to see if the MRI catches cancers that ultr…

This study is testing whether a simple finger-prick test done at home can replace the standard oral glucose tolerance test (OGTT) for diagnosing type 1 and type 2 diabetes. The standard test requires a vein drip and multiple blood draws over hours, which many people find uncomfor…

This study tests whether giving entire villages a malaria vaccine along with anti-malaria drugs can reduce malaria cases more than vaccines or drugs alone. About 10,000 people aged 6 months and older will take part. Researchers will track infections over two years to see which ap…

This study tests whether a digital sleep therapy program (Sleepio) can improve quality of life and movement in adults with fibromyalgia who also have trouble sleeping. About 142 participants will use the program at home for 10 weeks or receive standard sleep advice. Researchers w…

This study aims to develop new ways to find lung cancer earlier by analyzing blood samples with artificial intelligence. Researchers will collect blood from 5,000 people who have suspicious spots on their lungs. The goal is to create tools that help doctors diagnose lung cancer f…

This study tests whether 'Hope Groups' — a program offering mental health support, parenting help, and violence prevention — can improve the well-being of Palestinian caregivers displaced by war. About 490 participants from refugee camps will be randomly assigned to the program o…

This study looks at how a medication that blocks the brain chemical orexin affects emotions and learning in 62 healthy adults aged 18-40. Participants take a single dose of daridorexant or a placebo and then complete computer tasks measuring emotional responses and thinking skill…

This study explores whether a blood test that detects tiny DNA fragments from the tuberculosis bacteria can help doctors monitor how well treatment is working. Researchers will track 140 adults in Thailand with newly diagnosed TB, taking blood samples over time to see if the DNA …