University Of Missouri-columbia

This study tested whether high-dose fish oil supplements could improve nerve function in people with prediabetes and early diabetic neuropathy. Researchers planned to enroll 40 adults aged 55–80, but the trial was terminated early with only 31 participants. Participants took eith…

This study tested whether taking vitamin B2 (riboflavin) and getting natural sunlight could strengthen the cornea in people with keratoconus, a condition that causes the cornea to thin and bulge. The approach aimed to be a simpler, cheaper alternative to the standard cross-linkin…

This study tested whether cutting a specific tendon (the conjoint tendon) during reverse shoulder replacement surgery helps patients move their hand behind their back better. The trial planned to enroll 26 adults having their first reverse shoulder replacement, but it was termina…

Researchers at the University of Missouri-Columbia are testing whether warming lidocaine to 98 F makes it work better than room-temperature lidocaine for numbing the eye before intravitreal injections. The study includes 100 people who receive these injections for various eye con…

This study aimed to see if taking omega-3 supplements before and after major heart surgery could lower the chance of confusion (delirium) in patients aged 65 and older. The trial was planned for many participants but was stopped early after enrolling only one person. Because it e…

This small pilot study tested whether combining a gentle brain stimulation technique (tDCS) with a thinking-strategies training program could help people who had a stroke more than six months ago perform everyday activities better. Eleven participants were enrolled to see if the …

This study aimed to see if using a benzocaine spray before a lidocaine injection could reduce pain during IUD insertion. Participants were randomly assigned to receive different combinations of active drugs or placebos, and rated their pain on a scale. However, the trial was term…

This study tested a negative pressure vest (Biphasic Cuirass Ventilation) to see if it works as well as standard breathing masks for patients hospitalized with acute hypercapnic respiratory failure (high carbon dioxide levels). The trial planned to enroll 50 adults, but it was te…

This study tested a special pacifier that plays music or a mother's voice when a baby sucks correctly. It aimed to help premature infants with chronic lung disease learn to feed by mouth more quickly. The trial enrolled 33 babies but was stopped early, so the results are not conc…