University Of Melbourne

This study tests whether giving a clot-busting drug called tenecteplase directly into the brain artery after mechanical clot removal helps people recover better from a severe stroke. About 462 adults with a large vessel occlusion stroke will be randomly assigned to receive either…

This study tests a new, less invasive surgery to remove blood clots from the brain within 8 hours of a stroke caused by bleeding. About 240 adults with large brain bleeds will be randomly assigned to either the new surgery or standard medical care. The goal is to see if the surge…

This study tests if a special 12-week knee brace program works as well as surgery for people with a torn ACL. About 180 active adults aged 16-40 will be randomly assigned to either the brace or surgery group. Both groups will do physical therapy, and researchers will track knee p…

This study tests a clot-busting drug called tenecteplase in people who have a severe stroke caused by a blockage in the main artery at the back of the brain. The goal is to see if giving this drug within 24 hours of symptoms can improve recovery and reduce disability. About 688 a…

This large international trial is testing different treatments to lower the risk of death in people with a serious staph bloodstream infection. Up to 8,000 hospitalized adults will receive one of several experimental therapies. The main goal is to see which treatments improve sur…

This study is testing whether a single low dose of nivolumab, a drug used in cancer treatment, can reduce the hidden HIV reservoir in people living with HIV who are on antiretroviral therapy (ART). The HIV reservoir is a group of infected cells that stay dormant and prevent a cur…

This study compares two online treatments for Irritable Bowel Syndrome (IBS): a low-FODMAP diet that cuts out certain carbs, and exposure-based cognitive behavioral therapy that helps change unhelpful behaviors. Researchers want to find out which treatment works best for differen…

This study is for adults with hay fever living in South-Eastern Australia. Researchers want to find out who is most at risk for thunderstorm asthma, a dangerous condition that happens during spring pollen season. Participants will be tested for grass pollen allergy, do simple bre…