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New hope for deadly stroke: drug may restore blood flow hours later

NCT ID NCT05105633

First seen May 13, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This study tests a clot-busting drug called tenecteplase in people who have a severe stroke caused by a blockage in the main artery at the back of the brain. The goal is to see if giving this drug within 24 hours of symptoms can improve recovery and reduce disability. About 688 adults will be randomly assigned to receive either tenecteplase or standard care before any necessary clot-removal procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred Health

    RECRUITING

    Melbourne, Victoria, Australia

    Contact

    Contact

  • Austin Hospital

    RECRUITING

    Melbourne, Victoria, Australia

    Contact Email: •••••@•••••

    Contact

  • Bankstown-Lidcombe Hospital

    NOT_YET_RECRUITING

    Bankstown, New South Wales, Australia

    Contact

    Contact

  • Box Hill Hospital

    RECRUITING

    Melbourne, Victoria, Australia

    Contact

    Contact

  • Fiona Stanley Hospital

    RECRUITING

    Murdoch, Western Australia, 6150, Australia

    Contact

    Contact

  • Gold Coast Hospital

    NOT_YET_RECRUITING

    Gold Coast, Queensland, Australia

    Contact

    Contact

  • Grampians Health

    RECRUITING

    Ballarat, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Geral de Fortaleza

    RECRUITING

    Fortaleza, Brazil

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • John Hunter Hospital

    NOT_YET_RECRUITING

    Newcastle, New South Wales, Australia

    Contact

    Contact

  • Liverpool Hospital

    RECRUITING

    Sydney, New South Wales, Australia

    Contact

    Contact Email: •••••@•••••

  • Monash Health

    NOT_YET_RECRUITING

    Melbourne, Victoria, Australia

    Contact

    Contact

  • Northern Hospital

    RECRUITING

    Melbourne, Australia

    Contact Phone: •••-•••-••••

  • Princess Alexandra Hospital

    RECRUITING

    Woolloongabba, Queensland, 4102, Australia

    Contact

    Contact

  • Royal Adelaide Hospital

    RECRUITING

    Adelaide, South Australia, Australia

    Contact

    Contact

  • Royal Melbourne Hospital

    RECRUITING

    Melbourne, Victoria, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tours University Hospital

    RECRUITING

    Tours, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Western Health

    RECRUITING

    Melbourne, Victoria, Australia

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.