University Of Louisville
Clinical trials sponsored by University Of Louisville, explained in plain language.
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Shock and drug combo aims to get paralyzed patients stepping
Disease control OngoingThis early-phase study tests whether combining noninvasive spinal cord stimulation with a drug called buspirone can help people with severe spinal cord injuries take steps overground. Fifteen participants who have been paralyzed for at least a year will undergo various training a…
Phase: EARLY_PHASE1 • Sponsor: University of Louisville • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Spinal zap may help kids with paralysis grip again
Disease control ENROLLING_BY_INVITATIONThis study tests a noninvasive method called transcutaneous spinal cord stimulation (scTS) to help children aged 7-12 with chronic spinal cord injury improve hand function. Researchers will find the best placement and strength of stimulation on the neck and lower back, and compar…
Phase: NA • Sponsor: University of Louisville • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Study of magnesium for infant breathing trouble withdrawn before start
Symptom relief TerminatedThis study aimed to see if a single dose of magnesium sulfate could improve breathing in infants under 12 months old with moderate to severe bronchiolitis. Researchers planned to monitor respiratory status and check for side effects. However, the study was withdrawn before enroll…
Phase: PHASE2, PHASE3 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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New painkiller aims to replace opioids after knee surgery
Symptom relief ENROLLING_BY_INVITATIONThis study compares a new pain medicine called suzetrigine to the standard opioid oxycodone for pain after total knee replacement. About 140 adults with knee osteoarthritis will take either suzetrigine or oxycodone for two weeks after surgery. Researchers will measure pain levels…
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 18, 2026 11:58 UTC
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Spinal stimulation may boost breathing after injury
Knowledge-focused OngoingThis study looks at whether a non-invasive spinal cord stimulation device, combined with breathing, arm, or trunk exercises, can improve lung and muscle function in people with spinal cord injuries. Researchers will measure breathing strength and muscle activity before, during, a…
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated May 26, 2026 05:28 UTC