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Shock and drug combo aims to get paralyzed patients stepping

NCT ID NCT04105114

First seen Apr 06, 2026 · Last updated May 20, 2026 · Updated 6 times

Summary

This early-phase study tests whether combining noninvasive spinal cord stimulation with a drug called buspirone can help people with severe spinal cord injuries take steps overground. Fifteen participants who have been paralyzed for at least a year will undergo various training and measurement sessions over five years. The goal is to see if these techniques can trigger leg movement and improve walking ability.

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Contacts and locations

Locations

  • Frazier Rehabilitation and Neuroscience Institute

    Louisville, Kentucky, 40202, United States

Conditions

Explore the condition pages connected to this study.