University Of Louisville
Clinical trials sponsored by University Of Louisville, explained in plain language.
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Which bone putty works best for saving your jawbone after a tooth pull?
Disease control CompletedThis study tested two different bone graft materials (a mix of donated bone and a synthetic putty) to see which one better preserves the jawbone after a tooth is removed. Thirty adults who needed a tooth pulled and planned to get a dental implant took part. After 4 months, the re…
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Disease control
Last updated May 26, 2026 05:35 UTC
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Gum recession repair: does adding enamel protein help?
Disease control CompletedThis study looked at 24 adults with receding gums to see if adding an enamel protein to a standard gum graft procedure improves results. The standard method uses a tissue graft placed under the gum. Half the participants also got the enamel protein. Researchers measured gum cover…
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Disease control
Last updated May 26, 2026 05:30 UTC
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Virtual therapy tackles anorexia relapse by facing food and weight fears
Prevention CompletedThis study tested a virtual program called FED-F that helps people with anorexia nervosa face their fears about food, weight gain, body sensations, and social situations. The goal is to prevent relapse after intensive treatment. 70 adults who recently completed inpatient or resid…
Phase: NA • Sponsor: University of Louisville • Aim: Prevention
Last updated May 26, 2026 05:35 UTC
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Could a muscle peptide shield you from smog?
Prevention CompletedThis study tested whether taking carnosine, a natural supplement found in muscle and brain, can protect people from the harmful effects of air pollution. Researchers measured markers of oxidative stress and heart function in 299 adults living in the Louisville area. The goal was …
Phase: NA • Sponsor: University of Louisville • Aim: Prevention
Last updated May 01, 2026 16:01 UTC
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Phone app aims to ease disordered eating in women
Symptom relief CompletedThis study tested a smartphone app that provides personalized, self-guided treatment for women with disordered eating. Twenty women used the app to track their eating habits and received two tailored modules. Researchers measured changes in eating symptoms, anxiety, and quality o…
Phase: NA • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 26, 2026 05:25 UTC
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Can a muscle relaxant suppository ease pelvic pain?
Symptom relief CompletedThis study tested whether baclofen vaginal suppositories can reduce chronic pelvic pain in women. 39 women with chronic pelvic pain used either the baclofen suppository or a placebo nightly for 8 weeks. The goal was to see if pain scores and quality of life improved.
Phase: PHASE2 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 26, 2026 05:23 UTC
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Spinal stimulation may help bladder and blood pressure after injury
Knowledge-focused CompletedThis study looked at how spinal cord epidural stimulation affects bladder, bowel, and blood pressure control in 61 adults with spinal cord injury. Researchers monitored blood pressure during bladder and bowel tests, both in the lab and at home. The goal was to understand how the …
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated May 26, 2026 04:36 UTC
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Could a tailored approach beat standard therapy for eating disorders?
Knowledge-focused CompletedThis study compared a new personalized treatment for eating disorders to the current best therapy. 80 adults with conditions like anorexia or bulimia took part. The goal was to see if tailoring treatment to each person's unique needs works better and to understand how change happ…
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC
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Breaking the loop: could stopping negative thoughts lower blood pressure?
Knowledge-focused CompletedThis small study tested a type of talk therapy (RFCBT) that helps people break the cycle of repetitive negative thinking, called rumination. Researchers wanted to see if reducing rumination could also lower depressive symptoms and blood pressure in 9 low-income adults. The goal w…
Phase: NA • Sponsor: University of Louisville • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC