University Of Leipzig

This study tests whether using carbon dioxide gas instead of standard contrast dye during leg artery procedures can prevent serious kidney problems. About 1,960 people with blocked leg arteries and at moderate risk for kidney injury will be randomly assigned to receive either the…

This study tests whether using a special shockwave device to break up calcium in leg arteries works better than standard balloon angioplasty before placing a stent. About 120 people with severe peripheral artery disease and hardened blockages will be randomly assigned to one of t…

This study tests a simple technique called mucous fistula refeeding in 120 infants with an enterostomy (a surgical opening in the belly). The goal is to see if refeeding waste from the lower opening back into the gut helps babies reach full feeds faster after the second surgery t…

This study tests whether taking pancreatic enzymes (NORTASE®) improves quality of life and weight in people who have had most or all of their stomach removed. About 188 adults who had a gastrectomy will receive either the enzyme or standard care. The main goal is to see if the en…

This study aims to better understand how many calories a person needs to eat to stay in energy balance—where weight stays steady. Researchers will use a special room called a whole-room calorimeter to measure energy burned and compare it to standard formulas. 34 healthy adults wi…

This study looks at how testosterone and estrogen therapy changes metabolism, eating habits, and heart health in transgender individuals. Researchers will measure energy use, insulin sensitivity, and artery stiffness in 80 participants over time. The goal is to understand how sex…

This study will follow 1000 people recently hospitalized for worsening heart failure. Half will receive extra support from a heart failure care network, while the other half gets usual care. Researchers will measure changes in a key heart stress marker and quality of life over si…