University Of Leipzig

This study tests two approaches for treating complex blockages in the leg's main artery. One group gets a drug-coated balloon to open the artery without leaving a permanent stent, while the other group gets a stent. The goal is to see which method keeps the artery open longer and…

This study tests a shorter, 5-day course of azacitidine combined with venetoclax for adults with acute myeloid leukemia (AML) who cannot tolerate standard intensive chemotherapy. The goal is to see if the shorter regimen reduces side effects like infections and hospital stays whi…

This study looks at better ways to diagnose a type of heart failure called HFpEF in people who have shortness of breath but no clear cause. Researchers will compare simple tests to the standard invasive procedure to see which ones work best. The goal is to make diagnosis easier a…

This study compares a standard heart procedure called pulmonary vein isolation (PVI) to a fake (sham) procedure to see if the symptom relief in atrial fibrillation patients is real or just a placebo effect. About 262 adults with symptomatic atrial fibrillation will be randomly as…

This study follows 60 people with lower-risk myelodysplastic neoplasms (MDS) for 6 months to see how different blood transfusion strategies affect their quality of life and health costs. Participants use a smartphone app (or paper forms) to answer weekly questions about how they …

This study tests whether a smartwatch (Apple Watch or PulseOn) can detect hidden atrial fibrillation (AF) in 84 stroke patients who already have an implanted heart monitor. Participants wear the watch for 12 weeks, and the watch alerts them if it senses an irregular pulse, allowi…

This study follows 1,000 adults with dyslipidemia who have trouble tolerating statins. Researchers will track treatment changes, cholesterol levels, and quality of life to better understand this common condition. The goal is to improve prevention of heart disease in people who ca…