University Of Exeter

This study looks at whether a structured exercise program can help overweight and obese women aged 25-50 maintain muscle mass and physical function while taking the weight-loss drug tirzepatide. Participants will be split into two groups: one taking tirzepatide alone, and the oth…

This study tests a smart wearable device called gaitQ that uses cues to help people with long-term movement conditions like Parkinson's disease, stroke, multiple sclerosis, and arthritis walk better. Researchers will measure walking speed, step length, and safety in 150 participa…

This study aims to understand how inflammation affects the brain in Parkinson's disease. Researchers will give a mild inflammatory substance (LPS) to 30 participants, including people with Parkinson's and healthy volunteers, and use special brain scans to measure the response. Th…

This study looks at babies and young children who develop type 1 diabetes before age 2, a very rare and extreme form of the disease. Researchers want to understand what goes wrong with the immune system to cause diabetes so early. They will study blood samples and genes from 300 …

This study looks at how rare genetic changes affect beta cells, which control blood sugar. Researchers will compare people with and without these gene variants using blood tests and optional MRI scans. The goal is to find new biomarkers and understand the disease better, but ther…

This study aims to find a new marker for Parkinson's disease by using special brain scans (PET, SPECT, and MRI). Researchers will track 44 people over time to see how certain brain cells change as the disease progresses. The goal is to better understand Parkinson's, not to test a…

This study uses PET, SPECT, and MRI brain scans to better understand brain changes in Parkinson's disease. Researchers hope to find a biomarker that can help develop new medications to slow symptom progression. The study involves 42 adults aged 25-85 with Parkinson's disease.

This study uses special brain scans to measure damage to nerve connections in people with Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP). Researchers will scan 36 adults aged 45-80 at the start and after 12 months to see how the damage changes over time. T…

This study aims to find a biological marker for Parkinson's disease by using special brain scans (PET, SPECT, and MRI) in 45 people with certain genetic mutations. The goal is to better understand brain changes in Parkinson's and help develop new medications that could slow the d…

This study looks at whether a special high-protein sauce can help older adults absorb essential amino acids better than a regular low-protein sauce. Researchers want to see if the sauce provides more nutrition without making people feel too full. Twenty adults aged 60 and older w…