University Of Exeter

This study is testing whether a strength training program can help women keep their muscle mass while they lose weight using the medication tirzepatide. Researchers will recruit 60 overweight or obese women aged 25-50 and give them tirzepatide. Half will also follow a supervised,…

This study is testing a computer tool that scans patient records in family doctor offices to help identify people who may have been diagnosed with the wrong type of diabetes. The tool flags cases where diabetes classification might be incorrect, prompting doctors to review record…

This study is testing a smart wearable device called gaitQ, which is worn on the legs. It uses gentle vibrations to help people with long-term movement conditions like Parkinson's, stroke, and multiple sclerosis improve their walking, reduce freezing episodes, and potentially low…

This study is testing whether adding a plant-based, high-protein sauce to meals helps older adults absorb essential amino acids better than a regular low-protein sauce. Researchers want to see if this protein boost improves nutrition without making people feel uncomfortably full …

This study aims to find a measurable sign, or biomarker, of Parkinson's disease progression. Researchers will use specialized brain scans (PET, SPECT, and MRI) on 44 participants to look at chemical and structural changes over a one-year period. The goal is to better understand t…

This study investigates whether problems with the brain's natural waste-clearing system (called the glymphatic system) contribute to multiple sclerosis. Researchers will use MRI scans to compare this system in 30 people with early MS symptoms (clinically isolated syndrome) agains…

This study aims to understand why some babies develop type 1 diabetes before age two, which is very rare and aggressive. Researchers will compare these babies to children with more typical diabetes onset and to healthy children. By studying their immune systems, genes, and family…

This study aims to understand the role of brain inflammation in Parkinson's disease. Researchers will compare 30 people with Parkinson's to healthy volunteers. They will use special brain scans before and after giving a compound that causes a mild, temporary inflammatory response…

This study aims to understand how rare genetic changes cause problems with the body's insulin-producing cells, leading to conditions like diabetes or very low blood sugar. Researchers will compare detailed blood samples and optional body scans from 50 people who have these geneti…

This study aims to better understand Parkinson's disease by looking at brain chemistry and structure. Researchers will use advanced brain imaging scans (PET, SPECT, and MRI) on 42 participants aged 25-85 to identify biological markers of the disease. The findings could help guide…

This study aims to find a measurable sign, or biomarker, of Parkinson's disease using advanced brain scans. Researchers will scan 45 people who carry genetic mutations linked to Parkinson's to better understand brain changes. The goal is to gather knowledge that helps develop fut…

This study aims to better understand how two rare, progressive brain diseases—Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP)—damage the brain's nerve connections. Researchers will use specialized brain scans (PET and MRI) on about 36 participants to measur…