University Of Cincinnati

This trial tests whether a combination of two common antihistamines, cetirizine and famotidine, can reduce symptoms in people with diarrhea-predominant irritable bowel syndrome (IBS-D). Participants take the antihistamines or a placebo for 30 days, then switch, so each person ser…

This trial tests whether using a 3D-printed model of a patient's jaw before surgery helps surgeons repair a broken jaw faster and with more confidence. Half of the participants will have a model printed from their CT scan, and the plate will be bent to fit the model ahead of time…

This phase II trial tests an adaptive chemotherapy approach for people with pancreatic cancer that can be removed by surgery. The goal is to see if adjusting the chemo regimen based on early response can increase the number of patients who become eligible for surgery. About 32 pa…

This study tests a combination of an immunotherapy drug (pembrolizumab) and a type of internal radiation (cesium-131 brachytherapy) given during surgery for head and neck cancer that has come back. The goal is to see if this approach is safe and helps prevent the cancer from retu…

This study tests whether giving a lower dose of radiation to nearby lymph nodes can reduce side effects in people with anal cancer who are also receiving chemotherapy. The trial includes 33 adults with locally advanced anal cancer. The goal is to see if this approach lowers toxic…

This study looks at two new methods to tell apart blockages in large versus tiny heart arteries. About 68 adults with known or suspected coronary artery disease will get a PET scan and a heart catheterization. Researchers will compare the new measurements with standard tests to s…

This study tests a program called Healthy Eating for My Infant (HEMI) designed to prevent obesity in infants from low-income families. The program includes educational sessions and peer support to help mothers with feeding and mental health. Researchers will enroll 60 mother-infa…

This study tests a mobile app called RN-SLEEP that teaches night-shift nurses cognitive-behavioral strategies to improve sleep and reduce fatigue. 76 nurses will use either the RN-SLEEP app or a control app for several weeks. Researchers will measure sleep duration, quality, and …

This study tests a telehealth program called TASK III for people caring for a family member after a stroke. The program includes a resource guide and eight weekly calls from a nurse to help caregivers build skills and manage their own health. Researchers will measure changes in c…

Researchers at the University of Cincinnati are studying how brief electrical brain stimulation affects the brain waves that help us stay focused and switch between tasks. They will record brain activity from over 100 electrodes in adults with epilepsy who are already undergoing …