University Hospitals, Leicester

This study compares two pacing methods in 100 adults with atrial fibrillation and heart failure who need AV node ablation. The new method, HIS bundle pacing, aims to use the heart's natural electrical system to improve function and symptoms. Participants will be monitored for imp…

This study aims to find the genes that cause bicuspid aortic valve (BAV), a common heart defect where the valve has two flaps instead of three. Researchers will collect blood samples from 700 people with BAV and their family members to compare their DNA. Finding the genetic cause…

This study is testing a simple bedside test called bioimpedance to see if it can measure changes in body water content in pregnant women. Researchers will check if certain conditions like pre-eclampsia or heavy bleeding affect fluid balance. The goal is to learn more about hydrat…