Hunt for heart valve genes launches in 700 volunteers
NCT ID NCT04514445
First seen Mar 08, 2026 · Last updated Jun 17, 2026 · Updated 16 times
Summary
This study aims to find the genetic causes of bicuspid aortic valve (BAV), a common heart defect where the valve has two flaps instead of three. Researchers will collect blood samples from 700 people with BAV and their family members to compare DNA. The goal is to identify gene changes linked to the condition, which could lead to better understanding and future treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Imperial College Healthcare NHS Trust
RECRUITINGLondon, United Kingdom
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Kettering General Hospital
RECRUITINGKettering, United Kingdom
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Sheffield Teaching Hospital NHS Foundation Trust
RECRUITINGSheffield, United Kingdom
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University Hospitals of Leicester
RECRUITINGLeicester, United Kingdom
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.