University Children's Hospital, Zurich

This study tests a new material called NovoSorb BTM to help heal deep skin wounds, like those from burns or surgery. Researchers want to see if it makes the healed skin more elastic and improves quality of life compared to the usual treatment. About 42 people aged 1 to 75 will ta…

This study looks for a better way to diagnose Lyme disease in children early on. Current tests can miss the infection or give false positives. Researchers will test a new method that measures specific immune cells in the blood. Up to 502 children with suspected Lyme disease will …

This study looks at whether a short-arm cast works as well as a long-arm cast for children with certain forearm fractures (Salter-Harris I/II). About 120 kids aged 4 to 16 will be randomly assigned to one of the two cast types. The goal is to see if the shorter cast keeps the bon…

This study looks at children with large birthmarks (congenital melanocytic nevi) who choose to have them surgically removed. The goal is to see if removal improves their quality of life and reduces feelings of being stigmatized. About 100 children aged 9 months to 16 years will b…

This study looks at two different surgical methods for removing simple ovarian cysts in girls and teenagers. The goal is to find out which technique better protects the ovary's future function and lowers the chance of the cyst coming back. About 80 participants aged 1 to 18 with …

This study aims to find new genetic causes of primary immunodeficiency, a condition where the immune system doesn't work properly, leading to frequent or severe infections. Researchers will compare the genes of 500 people with suspected immunodeficiency, their relatives, and heal…

This study follows 21 adolescents aged 12-18 with post-traumatic stress symptoms to see how their symptoms change during trauma-focused cognitive behavioral therapy (TF-CBT). Researchers use a custom questionnaire that tracks each teen's most distressing symptoms. The goal is to …

This study is testing a new questionnaire called PTSD-iMPACT to see how well it measures the real-life struggles children and teens face due to PTSD. Researchers will ask 1200 young people and their caregivers in Switzerland and Germany about areas like school, friendships, and h…

This study aims to measure how well the body produces urea in healthy people and in patients with urea cycle disorders (UCDs). Researchers will use a safe, non-radioactive tracer to track urea production over a few hours. The goal is to create a reliable test that can help evalua…