Todd C. Lee Md Mph Fidsa

This study tests whether a lower dose of the antibiotic TMP-SMX works as well as the standard dose for treating a serious lung infection called PCP in people with weakened immune systems. The standard dose often causes severe side effects like liver injury or kidney failure. The …

This study tests whether adding ertapenem to the standard antibiotic cefazolin helps adults with methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infections recover faster. About 60 participants will receive either the combination or standard care. The goal is to …

This study looks at 300 adults with a serious staph bloodstream infection who already take aspirin for heart health. Researchers want to see if switching to clopidogrel, another heart drug that may also fight staph bacteria, leads to fewer complications or deaths. Participants ar…

This study compares two common antibiotics, daptomycin and vancomycin, to see which one works better for adults with MRSA bloodstream infections. About 300 participants will be randomly assigned to one of the two drugs. The goal is to find which treatment leads to fewer complicat…

This study looks at whether not giving the antibiotic rifampin is as safe and effective as giving it for people with a serious heart valve infection caused by S. aureus bacteria. About 330 adults with infected prosthetic heart valves will be randomly assigned to receive or skip r…