Could a lower dose of this antibiotic be safer and just as effective?
NCT ID NCT04851015
First seen Feb 28, 2026 · Last updated May 24, 2026 · Updated 13 times
Summary
This study tests whether a lower dose of the antibiotic TMP-SMX works as well as the standard dose for treating a serious lung infection called PCP in people with weakened immune systems. The standard dose often causes severe side effects like liver injury or kidney failure. The trial will compare the lower dose to the standard dose in 416 adults to see if it reduces side effects without affecting survival or recovery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital)
RECRUITINGMontreal, Quebec, H4A3J1, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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