Tianjin Medical University Second Hospital

This study tests whether a urine DNA test can help doctors decide how long to give immunotherapy for a severe type of bladder cancer that can't be fully removed with surgery. About 53 adults with very-high-risk non-muscle-invasive bladder cancer will receive immunotherapy, and th…

This study tests whether a combination of two drugs (tislelizumab and nab-paclitaxel) can treat renal pelvic cancer while avoiding removal of the kidney. About 35 adults with early-stage cancer that hasn't spread will receive the drugs, and if the tumor shrinks enough, they may g…

This study looks at whether removing nearby lymph nodes during standard surgery for high-risk upper tract cancer helps patients live longer without the cancer coming back. About 150 adults will be randomly assigned to get either the standard surgery alone or with lymph node remov…

This study tests an experimental drug called tunlametinib in 15 adults with advanced solid tumors (not melanoma) that have a change in the NRAS gene and have stopped responding to standard treatments. The goal is to see if the drug can shrink or control the cancer. Participants w…

This study tests two drugs (tislelizumab and disitamab vedotin) given before surgery to people with a rare, high-risk cancer of the upper urinary tract. The goal is to see if the combination can shrink or eliminate tumors, making surgery more effective. About 21 adults with HER2-…

This study tests if a combination of three treatments—a targeted procedure to block blood flow to the tumor, an immunotherapy drug, and a targeted therapy pill—can shrink advanced kidney cancer before surgery. About 40 adults with certain stages of kidney cancer will receive this…

This study tests two drugs, SKB264 and KL-A167, together in people with aggressive or neuroendocrine prostate cancer that has stopped responding to hormone therapy. The goal is to see if the combination can shrink tumors or slow the disease. About 28 adults who have already tried…

This study is for people with high-risk bladder cancer who need regular check-ups with a camera in the bladder (cystoscopy). The camera test is uncomfortable and can cause side effects. Researchers want to see if a non-invasive urine test that looks for cancer DNA can help decide…

This study tests whether a simple blood and urine test (liquid biopsy) can help diagnose, monitor treatment response, and predict recurrence in people with urothelial carcinoma (a type of bladder cancer). Researchers will compare these non-invasive tests to standard tissue biopsi…

This study looks at whether a urine test that detects tumor DNA and RNA can help doctors decide which high-risk bladder cancer patients truly need a second surgery. Currently, many patients undergo a repeat procedure, but it may not always be necessary. The goal is to see if the …

This study looks at whether a simple urine test that detects tumor DNA can identify bladder cancer patients who truly need a second surgery. About 196 adults with early-stage bladder cancer will be randomly assigned to have their repeat surgery decision guided by the urine test o…