The University Of Texas Medical Branch, Galveston

This study tests whether two doses of the HPV vaccine work as well as three doses for women aged 27 to 45. About 618 women will be randomly assigned to receive either two or three shots, and their immune response will be checked over 12 months. The goal is to see if a shorter vac…

This study compares a new, less invasive procedure called middle meningeal artery embolization (MMAE) to standard open surgery for treating chronic subdural hematoma (a type of brain bleed). About 520 adults aged 40-90 with moderate symptoms will be randomly assigned to one of th…

This study looks at whether involving the whole family can help people with type 2 diabetes in rural Kentucky eat healthier and exercise more. Researchers will work with 75 adults and their families to create a personalized nutrition and physical activity plan for 6 months. The g…

This study looks at whether a common dietary fiber called inulin can improve fatigue and thinking skills in people recovering from a brain injury. Researchers will track changes in gut bacteria and symptoms over six months. About 130 adults in a rehab program will take inulin dai…

This study tests whether sildenafil (the drug in Viagra) can reduce urine leakage in people with spinal cord injuries. About 24 adults will take sildenafil or a placebo for 4 weeks and track their daily bladder leaks. The goal is to see if this drug offers a new way to manage inc…

This study compares three methods to reduce pain during corticosteroid injections for hand, wrist, or elbow problems: no anesthesia, a vibrating device, or a cooling spray. About 165 adults will rate their pain during the injection to see which method works best. The goal is to f…

This study tests whether delivering lidocaine (with or without steroids) directly into an artery in the brain can relieve the intense headaches that often follow a bleeding aneurysm. Researchers will enroll 15 adults with mild-to-moderate brain bleeds to see if the procedure redu…

This study tests a new way to help people who have had a stroke walk more evenly. Participants will walk on a treadmill that can have two belts moving at different speeds, with gentle resistance and real-time feedback like sounds or visuals. The goal is to see which combination b…

This study looks at whether eating pistachios and attending a health education session can improve sleep in women aged 45-65 who have poor sleep. Participants will eat a snack daily for about a month, meet with a study therapist, and track their sleep. Researchers will measure ch…

This study explores the link between gut bacteria, fatigue, and thinking problems in people with cancer. Researchers will follow 250 adults for 6 months, analyzing stool samples and testing memory and attention. The goal is to better understand these connections, not to test a ne…

This study looks at how the bacteria in your gut might influence how well immunotherapy works for solid cancers. Researchers will collect stool samples from 16 people with advanced cancer who are already receiving standard immunotherapy. The goal is to understand the connection, …

This study looks at how a non-invasive brain stimulation technique called cortical priming affects the ability to learn leg movements in both healthy adults and people who have had a stroke. Researchers will measure changes in stepping speed and brain activity after five sessions…

This study looks at why some people lose muscle and strength after weight loss surgery, and why others regain weight. Researchers will track eating habits, grip strength, and body changes in 110 bariatric patients for a year. They will also study genes and metabolism to find fact…

This study compares two muscle relaxant drugs (rocuronium and cisatracurium) used during general anesthesia in people with chronic kidney disease. The goal is to see which drug leads to fewer lung complications after surgery. About 490 adults with kidney disease will take part to…