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Scientists investigate muscle loss after weight loss surgery

NCT ID NCT07178704

Knowledge-focused Sponsor: The University of Texas Medical Branch, Galveston Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study looks at why some people lose muscle and strength after weight loss surgery, and why others regain weight. Researchers will track eating habits, grip strength, and body changes in 110 bariatric patients for a year. They will also study genes and metabolism to find factors that affect success. Healthy volunteers are included for comparison.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients will be recruited from those electing to undergo bariatric surgery at the University of Texas Medical Branch.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria (Bariatric Surgery Patients): * Age: 18 to 65 years at time of consent * BMI: 35-65 kg.m-2 * Scheduled to undergo bariatric surgery at UTMB * All races and ethnic backgrounds * Ability to speak and read English * Subject has provided informed consent in a manner approved by the IRB and is willing and able to comply with the trial procedures. Exclusion Criteria (Bariatric Surgery Patients): * Fails the medical criteria for bariatric surgery. * Anemia (hematocrit \< 33 % or donated blood in the past 12 weeks.) * Recent (5 years or less) history of cancer * Systemic steroids or immunosuppressant use for 8 or more consecutive days in the past 6 months, or any use of anabolic steroids or growth hormones in the same period. * Body mass index \< 35 or \> 65 kg.m-2. * Acute infectious disease or chronic infection. * Pregnancy or breast-feeding. * Any medical condition that, in the opinion of the investigator, would place the subject at increased risk for participation. * History of prior non-compliance that would, in the opinion of the investigator, make it difficult for the subject to comply with the study procedures or follow the investigator's instructions. * Concurrent participation in another research study. * Use of an investigational agent in the 30 days prior to signing informed consent.

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Conditions

The condition(s) this trial relates to.

obesity disorder Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric surgery patients

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The University of Texas Medical Branch

    RECRUITING

    Galveston, Texas, 77555, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.