The University Of Texas Health Science Center, Houston

This study is testing whether deep brain stimulation (DBS) can help people with severe depression that hasn't improved with standard treatments like medication, therapy, or electroconvulsive therapy. Doctors will implant a small device, similar to a pacemaker, to deliver electric…

This study is testing whether reducing the standard amount of intravenous (IV) fat given to extremely premature babies can protect their developing brains from bilirubin, a substance that can cause damage. Researchers will compare brain function and development at age 2 in babies…

This study is testing whether a combination of advanced PET heart scans, intensive lifestyle coaching, and targeted medication is better at managing stable heart disease and preventing heart attacks than standard medical care. It involves about 1,085 adults aged 40 and older who …

This study is testing whether giving very premature babies a higher daily dose of vitamin D (800 IU) during their first 28 days of life improves their health compared to usual care. Researchers will measure vitamin D levels and check if the supplement helps the babies' lungs, bon…

This study is testing a telehealth program to help people control their blood pressure after a stroke. The program includes video check-ups with a care team and home blood pressure monitoring. Researchers want to see if this approach improves health and reduces racial disparities…

This study is testing whether a home compression pump can improve the body's natural fluid drainage system in people with leg swelling caused by vein problems. Researchers will compare 34 participants who use the pump daily for about a month against a group receiving standard car…

This study aims to find the best approach for treating hidden hernias that can't be felt during a physical exam. Researchers are comparing immediate surgery against watchful waiting in 252 patients to see which leads to better outcomes and fewer complications. The goal is to crea…

This study is testing whether an extremely intensive upper arm therapy program is practical and helpful for people living with long-term effects of a stroke. It involves six hours of daily therapy to try to improve arm movement, reduce disability, and boost quality of life. The r…

This study is testing a new program to help community health centers provide better long-term care for people who have survived cancer. It involves over 5,500 patients and their care teams. The goal is to improve screening for new cancers and make sure survivors get the recommend…

This study aimed to compare two different heart ablation techniques for people with a type of irregular heartbeat called atrial fibrillation. It planned to test if a newer, more targeted ablation method using advanced mapping technology was faster, safer, or more effective than t…

This study is testing a new material—a patch made from donated umbilical cord tissue—to repair spina bifida in unborn babies. The goal is to create a watertight seal over the spinal cord defect during a special prenatal surgery. Researchers hope this will lower the risk of seriou…

This program aims to help people with opioid addiction by quickly connecting them to treatment after an overdose or emergency room visit. It combines medication, counseling, peer support, and follow-up care. The goal is to see if this coordinated approach helps people start and s…

This study is testing whether a culturally tailored lifestyle program called Healthy Liver/Hígado Sano can help Hispanic adults with fatty liver disease lose weight and improve their liver health. Researchers will compare participants in the program to those receiving usual care …

This study aimed to test how well a new medical device called RetroPerc works during surgery to remove large kidney stones. The device was designed to help surgeons reach the kidney more quickly and accurately. The trial planned to measure success by how fast surgeons could acces…

This study aimed to see if a small, temporary ultrasound probe could help doctors make better and faster decisions for unstable patients in intensive care. The probe, placed down the throat for up to 72 hours, would give continuous pictures of heart function. Researchers planned …

This study is testing a new imaging method to see how the body's lymphatic system works. Researchers will use a special dye and camera to take pictures of the lymphatic system in healthy people and in people with conditions like lymphedema. The goal is to better understand these …

This study is testing if starting a simple home therapy early can prevent painful facial and neck swelling (lymphedema) in people who have finished treatment for head and neck cancer. Researchers will use special imaging to spot early signs of swelling and then have one group use…

This study aimed to see if patients could safely drink clear liquids up to one hour before gallbladder surgery, instead of fasting overnight. Researchers wanted to compare stomach contents, patient comfort, and recovery between the two fasting methods. The goal was to improve pat…

This study is testing whether a new at-home rehabilitation program works for stroke survivors in Texas' Rio Grande Valley. The program uses video exercises on a mobile device, supported by visits from a community health worker. Researchers want to see if this approach helps impro…

This study is testing an online group program designed to help people who have lived with spinal cord injuries for many years. The program aims to improve physical health, reduce pain, and enhance mental wellbeing and social connection. Researchers are comparing the online progra…

This study is testing a non-invasive therapy called auricular point acupressure to see if it can ease the pain, numbness, and tingling caused by chemotherapy. Researchers are enrolling 225 adult cancer survivors who have these symptoms. Participants will tape small seeds to speci…

This study aims to better understand the biology of different headache disorders, including migraines and cluster headaches. Researchers will use capsaicin (from chili peppers) and ice water to trigger mild, temporary pain responses in participants with headaches and healthy volu…

This study aimed to understand how a gentle, non-invasive ultrasound technique affects brain activity related to emotions and thinking in healthy volunteers. Researchers planned to use brain scans to see if the ultrasound could safely change activity in areas linked to mood. The …

This study aims to understand how the brain learns and remembers fear and avoidance behaviors. Researchers will measure brain activity and skin sweat responses in 150 healthy participants as they view images and learn to avoid mild shocks. The goal is to map the brain circuits in…

This research follows over 1,500 people for more than a decade to identify what factors increase or decrease the risk of gun access and use in dating relationships. The study combines surveys, interviews, and official records to understand why some people carry or use firearms in…