The University Of Texas Health Science Center, Houston
Clinical trials sponsored by The University Of Texas Health Science Center, Houston, explained in plain language.
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Diabetes drug tested as Double-Duty aid to quit smoking and stop weight gain
Disease control CompletedThis study tested if adding the diabetes medication exenatide to standard nicotine patches helps people quit smoking more successfully. It also checked if the medication could prevent the weight gain that often happens after quitting. The trial involved 140 adult smokers who want…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Can facebook and instagram keep kids with asthma out of the hospital?
Disease control CompletedThis study tested whether providing asthma education through social media platforms like Facebook and Instagram could help children manage their condition better. Researchers enrolled 200 children recently hospitalized for asthma and their caregivers, all of whom used social medi…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Shining a light on gum disease: can light therapy boost standard treatment?
Disease control CompletedThis study tested whether adding a special light therapy to the standard deep cleaning for gum disease improves results. Researchers compared the standard cleaning alone to cleaning plus the light treatment in 20 patients. They measured changes in gum bleeding, pocket depth, and …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Sleep or sedate? anesthesia choice could determine stroke recovery
Disease control CompletedThis study tested whether putting stroke patients fully to sleep (general anesthesia) or keeping them lightly sedated during emergency clot removal leads to better recovery. Researchers compared 260 patients with severe strokes to see which anesthesia approach resulted in less di…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Study tests best pill for dangerous Post-Birth blood pressure
Disease control CompletedThis study aimed to find out which of two common blood pressure medications works better for women with high blood pressure after giving birth. Researchers compared a combination pill (hydrochlorothiazide/lisinopril) against another standard medication (nifedipine) in 70 postpart…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Nerve zap & therapy: a new hope for regaining hand control?
Disease control CompletedThis small, early-stage study tested whether it's safe and practical to pair vagus nerve stimulation (a small implanted device) with intensive hand and arm rehabilitation for people with neck-level spinal cord injuries. Six participants had the device implanted and were randomly …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Can virtual cooking classes help fight diabetes and obesity?
Disease control CompletedThis study tested whether a series of online cooking and nutrition classes could help people with type 2 diabetes and a high body mass index (BMI) improve their health. 89 participants from specific clinics learned about healthy eating and cooking skills through virtual classes. …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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Brain study tests hormone boost for PTSD therapy
Disease control CompletedThis study tested whether adding an estrogen pill (estradiol) to a standard talk therapy called Prolonged Exposure could improve treatment results for women with PTSD. Researchers enrolled 83 women and randomly assigned them to receive either the therapy with estrogen or therapy …
Phase: PHASE3 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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New sensor could spot pregnancy diabetes sooner, protect moms and babies
Diagnosis CompletedThis study tested whether using a continuous glucose monitor (CGM) to screen for gestational diabetes works better than the usual one-time blood test. It involved over 1,600 pregnant women between 24-30 weeks. The goal was to see if the CGM method leads to fewer health problems f…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Diagnosis
Last updated Apr 03, 2026 14:41 UTC
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Rapid tests aim to catch hidden infections in pregnant women
Diagnosis CompletedThis study tested a new screening strategy in Guatemala. It used rapid, on-site tests to check pregnant women for syphilis and HIV during prenatal visits. The goal was to see if this approach could find more infections faster, so treatment could start sooner to protect both mothe…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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Can a computer class stop teen dating violence?
Prevention CompletedThis study tested a new online program called 'Me & You-Tech' designed to prevent teen dating violence. The program was given to 6th-grade students in some schools and compared to students in other schools who received their usual health education. Researchers wanted to see if th…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Apr 03, 2026 21:40 UTC
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Local health workers and text messages boost COVID testing in Hard-Hit communities
Prevention CompletedThis study tested whether a community-based program could increase COVID-19 testing and vaccination in vulnerable populations. Community health workers provided free rapid tests and sent educational text messages to 384 participants over 8 weeks. The goal was to see if this perso…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Apr 02, 2026 14:58 UTC
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Heartburn drug could shield kidneys in High-Risk heart surgery
Prevention CompletedThis study tested if giving the heartburn medicine pantoprazole during heart surgery could prevent a common and serious complication: sudden kidney injury. Researchers compared it to another medicine (famotidine) in 100 patients at high risk for this problem. The goal was to see …
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Apr 02, 2026 14:57 UTC
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Can free healthy food stop diabetes before it starts?
Prevention CompletedThis study tested whether adding a food incentive program to standard diabetes prevention classes helps people stick with the program and make lasting healthy changes. It involved 61 adults at risk for developing diabetes. The goal was to see if providing support for healthy eati…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Apr 02, 2026 14:56 UTC
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Can a school program stop teens from vaping? major study tests the waters
Prevention CompletedThis study tested whether a special classroom program called 'CATCH My Breath' could help prevent middle school students from starting to use e-cigarettes. Researchers compared the program to the usual health lessons in 20 schools, following about 1,400 students from 6th to 9th g…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Mar 31, 2026 12:12 UTC
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Does waiting to cut the cord cause more baby jaundice?
Prevention CompletedThis study looked at whether delaying the clamping of the umbilical cord after birth increases jaundice risk in newborns. It focused on babies already at higher risk because their mothers had a previous child who needed light therapy for jaundice. Researchers measured bilirubin l…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Can classroom moves boost Kids' health? new school strategy tested
Prevention CompletedThis study aimed to create and test a practical plan to help elementary school teachers use 'active learning' in their classrooms. Active learning involves short bursts of movement during lessons to increase children's physical activity. Researchers worked with over 300 teachers …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Mar 09, 2026 14:24 UTC
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Can online coaching ease MS symptoms for wheelchair users?
Symptom relief CompletedThis study tested whether a 16-week online exercise coaching program is practical and helpful for people with multiple sclerosis who use wheelchairs. Researchers enrolled 24 participants to compare the exercise program against a general wellness program. The main goals were to se…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 03, 2026 21:42 UTC
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Natural compound tested as add-on treatment for bipolar depression
Symptom relief CompletedThis study tested whether adding a supplement called palmitoylethanolamide (PEA) could help reduce depression symptoms in people with bipolar disorder. Thirty-four participants who were already taking standard mood-stabilizing medications received either PEA or a placebo for seve…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 03, 2026 21:41 UTC
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New tissue graft tested against standard shot for stiff, painful shoulders
Symptom relief CompletedThis study tested if a donated tissue graft (ActiveMatrix) works better than a standard steroid injection for treating frozen shoulder. It involved 56 adults with a recent diagnosis of frozen shoulder who had not yet received other treatments. Researchers compared how well each t…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Can a sleep pill help you quit smoking?
Symptom relief CompletedThis study tested whether a prescription sleep medication called suvorexant could help people quit smoking by reducing cravings, withdrawal symptoms, and stress. Fourteen daily smokers participated, taking either the drug or a placebo. Researchers measured their urge to smoke, st…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Pilot study tests drug for mysterious chronic diarrhea
Symptom relief CompletedThis study tested whether the drug crofelemer could help reduce diarrhea symptoms in adults with unexplained chronic diarrhea. Researchers also looked at which standard medical tests were most useful for finding a treatable cause of the diarrhea. The goal was to ease symptoms and…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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New approach aims to cut pill burden for dementia patients
Symptom relief CompletedThis study tested a new way to help doctors and caregivers decide which medications might be safely reduced or stopped for people living with dementia. It compared a patient-centered planning method against usual care. The goal was to lower treatment burden, improve shared decisi…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Could a common muscle relaxant cut opioid use after surgery?
Symptom relief CompletedThis study looked at whether giving the muscle relaxant methocarbamol by IV after spine surgery helps control pain and reduces the need for strong opioid painkillers. Researchers tracked the pain levels and medication use of over 1,200 adults for 6 hours after their surgery. The …
Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 31, 2026 12:10 UTC
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New anesthesia technique aims for smoother surgery start
Symptom relief CompletedThis study tested a new way to give anesthesia drugs to help place a breathing tube more easily at the start of surgery. Researchers compared this new method to the standard approach in 154 patients who were overweight or had potentially difficult airways. They measured how quick…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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Doctors test which surgical glue causes fewer skin rashes
Symptom relief CompletedThis study compared two types of surgical skin glue used to seal small incisions after minimally invasive abdominal surgery. Researchers wanted to see which glue caused fewer skin rashes (contact dermatitis) in the six weeks after surgery. They tested both glues on the same patie…
Phase: PHASE3 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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At-Home brain zapping tested for Alzheimer's agitation
Symptom relief CompletedThis small study tested whether a gentle, at-home brain stimulation treatment called tDCS is safe and acceptable for people with Alzheimer's disease who experience behavioral symptoms like agitation or apathy. Researchers worked with 3 patients and their caregivers to see if this…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Spray may protect injured brains during routine hospital care
Symptom relief CompletedThis study tested if a lidocaine spray given through a breathing tube could help prevent dangerous spikes in brain pressure when nurses suction mucus from the lungs of children with severe head injuries. It compared the spray to a liquid lidocaine drip and a saltwater drip in 10 …
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Simple leg lift could make anesthesia safer
Symptom relief CompletedThis study tested whether simply raising a patient's legs before general anesthesia could prevent dangerous drops in blood pressure. Researchers compared 200 patients who had their legs elevated to those who did not, measuring blood pressure changes and medication needs. The goal…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Study reveals best surgical path for permanent birth control recovery
Symptom relief CompletedThis study compared three different surgical approaches for permanent female sterilization to see which one leads to better recovery and patient satisfaction. Researchers followed 255 women to measure their pain levels, quality of recovery, body image, and overall satisfaction af…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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Massive survey seeks answers for mysterious daily headaches
Knowledge-focused CompletedThis study used an online survey to learn about the symptoms and treatments experienced by people with New Daily Persistent Headache (NDPH), a poorly understood condition. Over 800 patients who had been diagnosed by a doctor participated by answering questions online. The goal is…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Thousands of headache patients share their treatment experiences
Knowledge-focused CompletedThis study surveyed people with cluster headaches to learn which treatments work best and gather opinions on new treatments. Over 2,400 participants completed a single online questionnaire about their experiences. The goal is to collect real-world information to help guide future…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Hospital study aims to spot hidden elder abuse before patients go home
Knowledge-focused CompletedThis study tested whether a short screening tool could be easily used to spot signs of elder abuse, neglect, or financial exploitation in older adults while they were in the hospital. The goal was to identify patients who might be at risk and connect them with a specialized care …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC