The Children's Hospital Of Zhejiang University School Of Medicine

This early-stage study tests whether specially engineered immune cells (CAR-NK cells) can safely control B cell-related autoimmune diseases in children. The therapy targets two markers on faulty immune cells to reduce disease activity. Up to 12 children with conditions like lupus…

This study tests a new gene therapy called EXG110 for people with Fabry disease, a genetic condition that causes pain, organ damage, and other serious problems. The goal is to find a safe dose and see if it can help control the disease. About 12 people aged 7 and older with confi…

This early-stage trial tests a new treatment for children with severe systemic sclerosis, a rare autoimmune disease that causes skin thickening and organ damage. The therapy uses the patient's own immune cells, modified to target and destroy faulty B cells. The study will enroll …

This early-stage study tests a new treatment using specially engineered immune cells (CAR-NK cells) in 36 children with B-cell-related autoimmune diseases like lupus and IgA nephropathy. The goal is to see if these cells can safely control the disease by targeting and calming the…

This early-stage study tests a new, fast-made version of CAR-T cell therapy for people with severe lupus that hasn't responded to standard treatments. The therapy uses a patient's own immune cells, modified to target and calm the overactive immune system causing lupus. The main g…

This early-stage study is testing a new treatment for people with certain autoimmune diseases like lupus and kidney disease. The treatment uses specially engineered immune cells (CAR T-cells) that target and attack faulty immune cells causing the disease. The main goal is to chec…

This study tests a new treatment using specially engineered immune cells (CAR-NK cells) in children aged 5 and older with severe rheumatic diseases like lupus that have not responded to standard therapies. The cells are designed to target and destroy faulty immune cells that caus…

This early-stage study tests a new treatment called QT-219C, which uses specially engineered immune cells (CAR-T cells) to target and destroy faulty B cells that cause autoimmune diseases like lupus and kidney disease. The treatment involves a one-time infusion after a short chem…

This study looks at whether a special ultrasound with contrast dye can help doctors better diagnose abdominal diseases in children. About 108 kids with suspected belly problems will get this scan, and researchers will track how accurate it is. The goal is to create standard guide…

This study is tracking 1,000 children in China who are getting standard allergy shots for dust mite allergies. Researchers are using a detailed blood test to map each child's unique allergy profile. They want to see if children with allergies to many mite parts respond better to …

This study looks at how the immune system changes in children with lupus who are getting a special therapy called BiTE. It does not give any treatment itself, but instead collects blood samples over time to track immune cells and see how they relate to disease activity. The goal …

This study looks at why some childhood cancer survivors continue to have symptoms like fatigue, pain, and trouble sleeping. Researchers will ask 600 survivors aged 8-18 about their symptoms and collect stool samples to study gut bacteria. The goal is to find links between gut hea…