St. Joseph's Healthcare Hamilton

This study tests two digital treatment programs for substance use disorder in 20 adults recently released from Canadian prisons. Participants will use the programs for 6 months, and researchers will track how often they complete modules, whether they relapse, and if they return t…

This study tests whether a sedative called dexmedetomidine can help critically ill adults tolerate non-invasive ventilation (a mask that helps them breathe) and avoid needing a breathing tube or dying. About 846 patients with acute respiratory failure will receive either the drug…

This study tests a new way to perform robotic lung surgery for early-stage lung cancer. Surgeons use a special dye that makes healthy lung tissue glow green, so they can see exactly which part to remove and which to save. The goal is to remove only the small cancerous segment ins…

This study tests a 4-week mindfulness program for mothers with postpartum anxiety. It aims to reduce anxiety, improve emotion regulation, and increase body awareness using questionnaires and brain scans. About 50 mothers in their first year postpartum will participate.

This study tests a new way to perform lung cancer surgery for early-stage non-small cell lung cancer. Doctors will use a 3D computer model (Synapse 3D) and a green dye injected into the blood to see exactly which part of the lung needs to be removed. The goal is to make surgery m…

This study tests a new psychological therapy designed for people whose depression is linked to difficult childhood experiences. The therapy aims to improve mood, emotional control, and distressing thoughts. Researchers will also look at how the therapy affects the body by taking …

This study explores whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) is safe and tolerable for older adults with mild memory and thinking problems. Thirty participants aged 60-90 will receive one of three types of dTMS coils …

This study looks at whether certain common medications, known as QT-prolonging drugs, actually cause serious heart problems in hospitalized adults. Researchers will analyze data from nearly 1 million patients to see if these drugs are linked to heart issues like cardiac arrest or…

This study looks at whether DNA from blood, sputum, lung fluid, and breath can help find genetic changes in non-small cell lung cancer. Researchers will collect samples from 210 adults before and after surgery and follow them for 24 months to see if these tests can detect cancer …