St. Joseph's Healthcare Hamilton

This study tests two digital treatment programs for people recently released from prison who have a history of substance use problems. The goal is to see if these programs are practical and helpful in preventing relapse and return to prison. About 20 participants will use the dig…

This study tests if a cream called Multiprofen-CC can reduce pain in adults with hand osteoarthritis. About 42 people will use the cream and a placebo (inactive cream) for 2 weeks each, in random order. The goal is to see if the cream improves pain, hand function, and overall wel…

This study tests a 4-week mindfulness program for mothers with postpartum anxiety. It aims to reduce anxiety, improve emotion regulation, and increase body awareness using questionnaires and brain scans. The trial enrolls 50 mothers within 12 months of delivery.

This study tests a new psychological therapy designed for people whose depression is linked to difficult childhood experiences. The therapy aims to improve mood, emotional control, and distressing thoughts. Researchers will also look at biological changes in the blood. The trial …

This study tests a technique using a fluorescent dye to help surgeons see exactly which part of the lung to remove during robotic surgery for early-stage lung cancer. The goal is to remove only the small cancerous segment instead of an entire lobe, saving healthy lung tissue. Abo…

This study tests whether a sedative called dexmedetomidine can help critically ill adults tolerate non-invasive ventilation (a mask that helps breathing) and avoid needing a breathing tube. About 846 patients with acute respiratory failure will receive either the drug or a placeb…

This study tests a new way to remove small lung tumors using a 3D computer model and a dye that makes the tumor glow during surgery. The goal is to help surgeons remove only the diseased part of the lung, avoiding a full lobe removal. About 32 adults with early-stage lung cancer …

This study will analyze health records from nearly 1 million hospitalized adults to see if taking certain medications known to affect heart rhythm actually leads to serious heart events like cardiac arrest or dangerous arrhythmias. Researchers want to find out which patients are …

This study looks at whether DNA from blood, sputum, lung fluid, and breath can help track non-small cell lung cancer before and after surgery. About 210 adults having surgery to remove their lung cancer will provide samples over 24 months. The goal is to see if these samples are …

This study is creating a large, standardized database of biomarker information from 900 people with mood disorders like depression and bipolar disorder. The goal is to help doctors and researchers better match treatments to individuals, reducing the time it takes to find an effec…

This study tests whether a non-invasive brain stimulation technique called deep TMS is safe and tolerable for older adults with mild memory or thinking problems. Thirty participants aged 60-90 will receive one of three types of stimulation coils. Researchers will track side effec…

This study looks at whether teaching college women who diet about how the body naturally controls weight can change their beliefs about weight control and improve body image and self-esteem. About 150 undergraduate dieters will take part in one of three education programs. The go…