St. Joseph's Healthcare Hamilton

This study tests whether a sedative called dexmedetomidine can help critically ill adults tolerate non-invasive ventilation (a mask that helps them breathe) and avoid needing a breathing tube or dying. About 846 patients with acute respiratory failure will receive either the drug…

This pilot study tests whether two digital treatment programs can help people recently released from prison manage substance use problems and avoid returning to jail. Researchers will follow 20 participants for 6 months to see if they use the programs and whether they relapse or …

This study tests a new psychological therapy designed for people whose depression is linked to difficult childhood experiences. The therapy aims to improve mood, emotional control, and distressing thoughts. Researchers will also look at how the therapy affects the body by taking …

This study looks at whether DNA from blood, sputum, lung fluid, and breath can help find genetic changes in non-small cell lung cancer. Researchers will collect samples from 210 adults before and after surgery and follow them for 24 months to see if these tests can detect cancer …

This study explores whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) is feasible and tolerable for older adults with mild memory or thinking problems. Thirty participants aged 60-90 will receive one of three types of dTMS coi…