Southeast University, China

This study tests whether using a special imaging tool (EIT) to set ventilator pressure (PEEP) improves survival in people with moderate-to-severe ARDS. About 2400 adults will be randomly assigned to EIT-guided PEEP or standard PEEP based on oxygen levels. The main goal is to see …

This study looks at two ways of feeding patients with severe lung injury (ARDS) who are lying on their stomachs and on a breathing machine. It compares feeding through a tube in the stomach versus one in the small intestine. The goal is to see which method helps patients get bett…

This study tests whether switching critically ill patients from full breathing machine support to a partial support mode within 6 hours helps them breathe on their own sooner. About 1,600 adults in ICUs who need a breathing tube for at least 2 days will take part. The goal is to …

This study looks at whether a sedative called remimazolam can help people in the intensive care unit (ICU) who are on breathing machines. Researchers will compare remimazolam to standard care in 80 adults to see if it leads to more days without a ventilator and fewer complication…

This study looks at how a specific part of the breathing cycle (the time it takes for the lungs to empty) affects how air and blood flow are matched in the lungs of patients with ARDS. Researchers will use a special imaging technique (EIT) to measure these changes in 60 adults on…

This study watches 1,000 adults in intensive care with severe lung failure (ARDS) who are placed face down to help them breathe. Researchers want to learn who benefits most, whether it is safe for patients with brain injuries, and when to stop. The goal is to create better guidel…

This study looks at 406 adults with acute brain injury who need a breathing machine. The goal is to find clues that help doctors know when it's safe to remove the breathing tube. By understanding these clues, the study hopes to reduce failed extubations and improve care for these…

This study observes 1500 adults with acute brain injury who need a breathing machine (ventilator) in the ICU. The goal is to understand how and when they can safely stop using the ventilator. Researchers hope this will help reduce complications and improve care for these patients…

This study looks at 500 adults with a severe lung condition called ARDS to see if they can be grouped into two types based on inflammation. The goal is to find out if knowing a patient's subtype helps doctors choose better treatments, like fluids or steroids. This research does n…