Southeast University, China

This study tests whether a personalized weaning plan can help adults with long-term health problems (like heart disease or COPD) get off breathing machines sooner. About 1380 participants will either receive standard care or a tailored approach that identifies the main reason for…

This study tests whether the steroid dexamethasone, when added to standard care, can lower the chance of death within 90 days for adults with severe lung injury caused by sepsis. About 1,474 patients on breathing machines will receive either dexamethasone or a placebo. The goal i…

This study tests whether a traditional Chinese herbal formula, Xuanbai Shengmai Decoction, can improve survival in adults with acute respiratory distress syndrome (ARDS), a severe lung condition often seen in the ICU. About 308 participants will receive either the herbal decoctio…

This study looks at how safe and effective the antifungal drug liposomal amphotericin B is for patients with a severe fungal infection called invasive aspergillosis who also have liver problems. The study will enroll 40 adults in intensive care in China. Researchers will measure …

This study tests whether a procedure using a thin, flexible tube (bronchoscopy) to clear mucus from the lungs can improve lung function in patients on breathing machines who have collapsed lung areas. About 104 adults will be randomly assigned to either standard care or standard …

This study looks back at medical records from 2,000 adults on breathing machines in the ICU. Researchers want to understand how nutrition-related blood tests change over time and how they relate to patient outcomes like survival and length of hospital stay. The goal is to create …

This study looks at how different non-invasive breathing supports (high-flow oxygen, masks, and continuous pressure) affect lung function in 60 adults with acute hypoxemic respiratory failure. The goal is to see which method best reduces uneven air movement in the lungs, called p…

This study will use a new 3D imaging technique (EIT) to observe how blood flow in the lungs switches on and off in a cycle during mechanical ventilation. The goal is to see if this pattern can be detected in 40 adults with moderate to severe ARDS. No treatment is given; the study…