Shanghai Ninth People's Hospital Affiliated To Shanghai Jiao Tong University

This study compares a personalized two-step calcium method to a standard approach for preventing blood clots during continuous kidney dialysis in 142 adults with acute kidney injury or advanced chronic kidney disease who also have liver failure or poor circulation. The goal is to…

This study tests a two-step treatment for people with salivary gland cancer that has come back or spread. First, patients get an antibody-drug conjugate (ADC) that delivers chemotherapy directly to cancer cells. If the disease stabilizes or only a few new spots appear, they also …

This study tests whether adding the drug benmelstobart to standard radiation and nimotuzumab can help prevent head and neck cancer from returning after surgery. About 386 adults with intermediate-risk features (like advanced tumor stage or close surgical margins) will be randomly…

This study tests a combination of three drugs (pucotenlimab, lenvatinib, and temozolomide) given before and after surgery for people with a rare type of skin cancer called head and neck mucosal melanoma. The goal is to see if this approach can shrink tumors and improve outcomes. …

This study tests whether mixed reality (MR) technology can help surgeons remove oral cancer and rebuild the area more precisely. Thirty people with oral cancer will be split into three groups: one using MR goggles, one using a virtual surgical guide, and one having standard surge…

This study looks at whether people with advanced head and neck cancer who respond well to immunotherapy can have a smaller, less damaging surgery instead of the standard extensive surgery. The goal is to see if the smaller surgery can preserve quality of life and organ function w…

This study tests a new AI system (PerioAI V2.0) that combines 3D mouth scans and X-rays to create a detailed map of gum disease. Researchers will enroll 80 adults with moderate-to-severe periodontitis to see if the AI can accurately identify bone defects and measure disease sever…

This study will check if simple methods like mouth photos, smartphone images, X-rays, and questionnaires can accurately find gum disease compared to a standard dental exam. About 2,000 adults will take part across five centers. The goal is to develop AI tools that make screening …

This study looks at whether using a laser to thin the outer shell of a frozen embryo (called laser-assisted hatching) can help women aged 35 and older get pregnant and have a baby. About 916 women will be randomly assigned to receive the laser treatment or standard care. The main…

This study compares two high-tech methods for placing dental implants in the front upper jaw: a robotic system and a dynamic navigation system. The goal is to see which one places the implant more accurately, takes less time, and makes patients more comfortable. Twenty-four adult…

This study compares two advanced methods for placing dental implants in people missing back teeth on one side: robotic-assisted surgery and static guide surgery. The goal is to see which approach places implants more accurately and improves patient outcomes. About 112 adults will…

This study tests whether digital dental impressions are as accurate as traditional putty impressions for people with no teeth who need implant-supported dentures. About 24 adults aged 30-80 will get one type of impression and visit the clinic 6 times. Researchers will check how w…

This study looks at whether transferring an embryo on day 2 or day 3 after fertilization leads to more live births in women aged 35 or older with low egg supply. About 470 women will be randomly assigned to one of the two transfer days. The goal is to find the best timing to impr…