Shanghai Ninth People's Hospital Affiliated To Shanghai Jiao Tong University

This study is testing whether patients with advanced head and neck cancer who respond well to initial immunotherapy can safely have less extensive surgery. The goal is to see if this 'de-escalated' surgery preserves more normal tissue and function—like speaking and swallowing—wit…

This study is testing a combination of three drugs (pucotenlimab, lenvatinib, and temozolomide) given before and after surgery for a rare type of head and neck melanoma. The goal is to see if this approach can shrink tumors effectively and safely before they are surgically remove…

This study is for people with high-risk head and neck cancer who have had surgery but cannot take the standard chemotherapy drug cisplatin. It will test if adding two newer drugs (nimotuzumab and bemcentinib) to standard radiation therapy after surgery is better at keeping the ca…

This study aims to find out if easier methods like smartphone photos, dental X-rays, and questionnaires can accurately detect gum disease, compared to a traditional dental exam. It will enroll 2,000 adults at five centers to test these methods, using artificial intelligence (AI) …

This study aims to see if new digital scanning technology is as accurate as traditional putty molds for creating custom dental implants for people who have lost all teeth in a jaw. Researchers will compare the fit of the final implant framework made from each type of impression. …

This study aims to find easier, less invasive ways to detect gum disease. Researchers will test whether photos, X-rays, saliva tests, and questionnaires can accurately identify gum problems compared to traditional dental exams. They'll recruit 2,000 dental patients across five in…

This study is testing whether mixed reality technology, similar to advanced video game graphics, can help surgeons perform more precise operations for oral cancer. Thirty patients will be randomly assigned to have surgery using the new mixed reality goggles, a computer guide, or …