Shanghai Mental Health Center

This study tests whether a non-invasive brain stimulation technique called targeted temporal interference stimulation (tTIS) can reduce drug cravings and improve decision-making in people with methamphetamine use disorder. About 60 adults aged 18-55 who have used methamphetamine …

This study tests a new, non-invasive brain stimulation technique called tTIS to see if it can reduce cravings for alcohol. Researchers will target the amygdala, a brain area linked to emotion and addiction. Sixty adults with alcohol use disorder will participate, and the study wi…

This study tests whether a non-invasive brain stimulation technique called tACS can help people with gambling disorder. Researchers will treat 60 adults and track changes in gambling symptoms, mood, and anxiety over three months. The goal is to see if this approach can improve se…

This study will test whether an artificial intelligence (AI) system can diagnose anxiety disorders just as accurately as a psychiatrist. One hundred adults with anxiety will be evaluated by both the AI and a specialist, and the results will be compared. If successful, this techno…

This study will test whether an artificial intelligence system can diagnose depressive disorders as accurately as a psychiatrist. One hundred adults aged 18 to 60 with depression will be evaluated by both the AI and a specialist. The goal is to see if the AI's diagnostic ability …

This early-stage study tests whether a nasal spray made from neural stem cell exosomes (tiny particles that carry cell messages) is safe for people with moderate-to-severe early-onset Alzheimer's. Nine adults aged 50-75 will receive the spray at different frequencies for 28 days.…

This early study tests whether a gentle electrical current applied to the scalp can help people with alcohol use disorder feel less urge to drink. Eighteen adults will receive the stimulation and report changes in cravings and drinking habits. The goal is to see if this non-invas…

This study tests a non-drug treatment called transcranial electrical stimulation (tES) for people who have both depression and chronic pain. 240 adults will receive either real or sham brain stimulation for 2 weeks. Researchers will measure changes in pain and mood to see if this…

This study will test whether adding an AI-based rehabilitation program to standard treatment helps people with anxiety disorders more than standard treatment alone. About 158 adults aged 18-60 with anxiety will participate. The main goal is to see if anxiety symptoms improve more…

This study looks at 130 adults with major depression and suicidal thoughts to understand how rapid treatments like Esketamine and electroconvulsive therapy (ECT) change the brain. Researchers will use brain scans, genetic tests, and blood samples to find markers that predict who …

This study looks at why people with OCD have strange or uncomfortable feelings (called sensory phenomena) and whether a type of brain stimulation can help. Researchers will use brain scans and EEG to compare people with OCD and healthy volunteers. They will also test if low-frequ…