Shanghai Mental Health Center

This study tests a non-invasive brain stimulation technique called targeted temporal interference stimulation (tTIS) aimed at the caudate nucleus. The goal is to reduce drug cravings and improve decision-making in 60 adults with methamphetamine use disorder. Participants will rec…

This trial tests whether online group dialectical behavioral therapy (DBT) is as effective as traditional face-to-face group DBT for women with bulimia nervosa. Participants will be randomly assigned to either 12 weeks of online or in-person group therapy, and researchers will co…

This study tested a new way to stimulate the brain in people addicted to amphetamines. Nine adults received closed-loop transcranial alternating current stimulation (tACS), which adjusts the stimulation based on their real-time brain activity. The goal was to improve executive co…

This study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce methamphetamine use in people already receiving methadone maintenance therapy. Fifty-five adults with both opioid and methamphetamine use dis…

This study tests whether deep brain stimulation (DBS) — a device that sends electrical pulses to specific brain areas — can help people with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. Participants receive a DBS implant targeting two …

This study tested a brain stimulation technique called closed-loop tACS in 21 people with methamphetamine addiction. The device uses brain wave patterns to deliver targeted electrical stimulation aimed at reducing cravings. Researchers measured craving levels and impulse control …

This pilot study tested a new type of brain stimulation, called accelerated intermittent theta burst stimulation (aiTBS), for people with anxiety disorders or PTSD. Fifteen participants received the non-invasive treatment targeting a novel brain area. The study measured changes i…

This study tested whether low-intensity ultrasound waves aimed at a specific brain area could help reduce negative symptoms of schizophrenia, such as lack of motivation and social withdrawal. 78 adults with stable schizophrenia received either real or fake ultrasound over 20 days…

This study tested two ways to deliver cognitive behavioral therapy (CBT) for binge eating: a web-based self-help program and online group therapy. 120 adults with bulimia or binge eating disorder took part. The goal was to see which approach better reduces binge eating episodes a…

This study tested whether a stepped-care internet-based cognitive behavior therapy (ICBT) with reduced support is as effective as traditional group therapy for obsessive-compulsive disorder (OCD). 95 adults with moderate to severe OCD took part. The goal was to see if the online …

This study tested a personalized brain stimulation technique for people with insomnia. Twenty adults received 10 days of treatment, and researchers measured sleep quality and mood changes. The goal was to see if this approach could ease insomnia symptoms.

Researchers are testing whether a non-invasive brain stimulation technique called high-definition transcranial alternating current stimulation (HD-tACS) can change brain wave activity in people with schizophrenia who hear voices. The study compares patients with auditory hallucin…

This study compares an AI-powered virtual agent to traditional teacher-led classes for teaching mental health literacy to 360 adolescents aged 11-18 in Shanghai. Over 6 weekly sessions, researchers will measure changes in mental health knowledge, attitudes, and help-seeking behav…

This study uses brain scans to investigate how meditation alters brain networks and fluid flow. Healthy adults interested in meditation will listen to guided audio instructions while undergoing MRI. The goal is to understand the brain's functional changes during meditation, not t…