Rwth Aachen University

This study tests whether adding a precise, high-dose radiation treatment (SBRT) after a standard liver cancer procedure (TACE) can better control tumors that cannot be surgically removed. About 30 adults with early- to intermediate-stage liver cancer will receive the combination …

This study tests whether a personalized treatment with Pentaglobin (a mix of antibodies) can improve recovery in people with severe abdominal infection (peritonitis) that has led to sepsis or septic shock. About 200 adults will receive either standard care or standard care plus P…

This study looks at how well the diaphragm works in 800 people with lung diseases like asthma, COPD, fibrosis, or pulmonary hypertension. Researchers want to understand if diaphragm problems are linked to shortness of breath. No new treatments are being tested—this is an observat…

This study looks at why the sympathetic (fight-or-flight) nervous system is overactive in people with COPD. Researchers will measure nerve signals, heart rate, and blood pressure in 135 adults with COPD. The goal is to understand how sleep apnea, lung function, and inflammation c…

This study is building a large database of information from 5,000 people with early memory problems or dementia in Germany. Researchers will collect medical data and fluid biomarkers over time to understand how the disease progresses and how it is currently diagnosed and treated.…

This study enrolls 25 active smokers who need a biopsy for a suspicious lung nodule. Researchers offer smoking cessation support and measure nicotine levels using urine tests and blood gas analysis. The goal is to see how many patients successfully quit smoking over 3 months. Thi…

This study looks at how the diaphragm—the main breathing muscle—weakens in patients on a breathing machine (mechanical ventilation) in the ICU. Researchers will use mild nerve stimulation and ultrasound to measure muscle strength and brain control over time. The goal is to unders…