Rwth Aachen University

This study tests whether a personalized treatment with Pentaglobin (a mix of antibodies) can improve recovery in people with severe abdominal infection (peritonitis) that has led to sepsis or septic shock. About 200 adults will receive either standard care or standard care plus P…

This study tests whether adding targeted radiation therapy after a standard liver cancer procedure (TACE) can better control tumors in people with early or intermediate-stage liver cancer who cannot have surgery. About 30 adults aged 18-80 with 1-3 tumors (at least 4 cm total) wi…

This study helps smokers who have a suspicious lung nodule quit smoking before they undergo a biopsy (bronchoscopy or CT-guided puncture). Researchers will offer smoking cessation support and track progress using urine tests and blood gas measurements. The goal is to see how many…

This study is creating a large database of 5,000 people in Germany who have early memory problems or dementia. Researchers will collect medical information and biomarkers over time to see how the disease progresses and how it is currently treated. The goal is to better understand…

This study looks at how the diaphragm—the main breathing muscle—weakens in patients on a breathing machine (mechanical ventilation) in the ICU. Researchers will use mild nerve stimulation and ultrasound to measure muscle strength and brain control over time. The goal is to unders…

This study looks at why the sympathetic (fight-or-flight) nervous system is overactive in people with COPD. Researchers will measure nerve activity, heart rate, and blood pressure in 135 adults with COPD. The goal is to understand how sleep apnea, lung function, and inflammation …

This study looks at how well the diaphragm works in 800 people with lung diseases like asthma, COPD, fibrosis, and pulmonary hypertension. Researchers want to see if diaphragm problems are linked to shortness of breath. Participants will do walking and sitting tests to measure br…