Post Graduate Institute Of Medical Education And Research, Chandigarh

This study tests whether adding empagliflozin (a diabetes drug) to standard carvedilol treatment can prevent serious liver complications and death in people with cirrhosis and a stiff heart condition. About 400 adults aged 18-65 with cirrhosis and left ventricular diastolic dysfu…

This study tests whether using a bedside heart ultrasound (POCUS) to guide fluid and medication decisions improves outcomes for 140 adults with liver cirrhosis and severe sepsis or septic shock, compared to standard guideline-based care. The goal is to give just enough fluids to …

This study looks at people with a lung condition caused by the fungus Aspergillus that has features of both chronic infection and allergy. It compares treatment with just an antifungal pill (itraconazole) versus that pill plus steroids. The goal is to see which approach works bet…

This study looks at whether feeding through a tube into the small intestine is better than eating by mouth for patients who have had a procedure to drain a fluid collection in the pancreas. About 50 adults with pancreatitis will be randomly assigned to one of two feeding methods.…

This study tests whether pregabalin, a drug used for nerve pain, can reduce severe itching in people with type 2 diabetes. About 46 adults will receive either pregabalin plus moisturizer or a placebo plus moisturizer for 12 weeks. Researchers will measure itching severity and qua…

This study tests if a sedative called dexmedetomidine works better than the standard midazolam for people undergoing a lung procedure called medical thoracoscopy. The goal is to see if it reduces pain, the need for extra pain medicine, and recovery time. About 56 adults with unex…

This study looks at whether tiny plastic particles (microplastics and nanoplastics) build up in the liver and worsen cirrhosis and heart problems. Researchers will compare tissue samples from 30 people with cirrhosis to those without liver disease. The goal is to understand how p…

This study looks at 150 pregnant women in India to understand how bile acids and genetic changes relate to intrahepatic cholestasis of pregnancy (ICP), a liver disorder causing severe itching and pregnancy risks. Researchers will compare women with and without ICP using blood tes…