Philipps University Marburg

This study tests a two-week smartphone app program designed to help people who have trouble feeling pleasure (anhedonia), along with symptoms of depression, anxiety, and stress. Participants will do three short daily exercises, such as savoring positive moments or practicing grat…

This study looks at whether adding positive mental rehearsal to a single session of exposure therapy can help people with high social anxiety feel better. About 40 participants will go through a standardized exposure training and then either do standard or positive mental rehears…

This study compares two new group therapies for major depression: one that helps people change rigid negative expectations, and another that boosts sensitivity to positive experiences. 150 adults with depression will be randomly assigned to one of these therapies or a waiting lis…

This study tests whether adding a guided imagery exercise after a single virtual reality (VR) speech session helps people with public speaking anxiety feel less fearful in new speaking situations. About 48 adults with high speech anxiety will do one VR speech, then either mentall…

This study tests whether enoxolone, a compound from licorice, can improve depression symptoms in people with unipolar depression. Researchers will check if certain biological markers (like hormone levels and blood pressure) predict who responds better to enoxolone versus a placeb…

This study tests whether a simple mental exercise—imagining yourself approaching a feared social situation—can increase motivation and pleasure in people with social anxiety. About 58 participants will learn about anxiety and then either practice mental imagery or a verbal reason…

This study tests a new way of caring for people with new-onset stable chest pain who might have coronary artery disease. Instead of going straight to cardiac catheterization, the new model uses a heart CT scan first, which is less invasive. About 3,369 participants across 16 regi…