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New heart care model could replace unnecessary procedures

NCT ID NCT07476040

Disease control Sponsor: Philipps University Marburg Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new way of caring for people with new-onset stable chest pain and suspected coronary artery disease. Instead of using a standard invasive heart catheterization, the new model uses a CT scan of the heart, which is less burdensome. The study will include about 3,369 participants across 16 regions in Germany to see if this approach reduces heart attacks, strokes, and other major heart problems while also lowering healthcare costs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 3,369 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥30 years * Suspected CAD with stable chest pain * Ability to give informed consent Exclusion Criteria: * Known or previously treated (with PCI or CABG) obstructive CAD (defined as at least one coronary diameter stenosis ≥50%) * Acute coronary syndrome * Negative invasive coronary angiography or coronary CT within the last 5 years * Already enrolled in the study * Not covered by statutory health insurance * Unable to give consent

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease (CAD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    39 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Charité - Universitätsmedizin Berlin, Klinik für Radiologie

    RECRUITING

    Berlin, 10117, Germany

  • Charité-Universitätsmedizin Berlin, Institut für Allgemeinmedizin

    RECRUITING

    Berlin, 10098, Germany

  • Christian-Albrechts-Universität zu Kiel, Medizinische Fakultät, Institut für Allgemeinmedizin

    RECRUITING

    Kiel, 24105, Germany

  • Georg-August-Universität Göttingen, Universitätsmedizin, Institut für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Göttingen, 37075, Germany

  • Goethe-Universität Frankfurt am Main, Institut für Allgemeinmedizin

    RECRUITING

    Frankfurt, 60590, Germany

  • Herzzentrum Leipzig, Abteilung für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Leipzig, 04289, Germany

  • Institut für Allgemeinmedizin des Universitätsklinikums Jena

    RECRUITING

    Jena, 07743, Germany

  • Philipps University Marburg, Institut für Allgemeinmedizin

    RECRUITING

    Marburg, 35043, Germany

  • RHOEN-Klinikum AG, Campus Bad Neustadt, Klinik für Radiologie

    RECRUITING

    Bad Neustadt an der Saale, 97616, Germany

  • RNS Gemeinschaftspraxis für Radiologie und Strahlentherapie

    RECRUITING

    Wiesbaden, 65189, Germany

  • Radiologische Allianz Hamburg

    RECRUITING

    Hamburg, 20095, Germany

  • Röntgeninstitut

    RECRUITING

    Düsseldorf, 40476, Germany

  • Uniklinik Köln, Institut für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Cologne, 50937, Germany

  • Universität Leipzig, Institut für Allgemeinmedizin

    RECRUITING

    Leipzig, 04103, Germany

  • Universität Würzburg, Institut für Allgemeinmedizin

    RECRUITING

    Würzburg, 97080, Germany

  • Universitätsklinikum Augsburg, Diagnostische und Interventionelle Radiologie und Neuroradiologie

    RECRUITING

    Augsburg, 86156, Germany

  • Universitätsklinikum Augsburg, Institut für Allgemeinmedizin

    RECRUITING

    Augsburg, 86156, Germany

  • Universitätsklinikum Düsseldorf, Institut für Allgemeinmedizin (ifam)

    RECRUITING

    Düsseldorf, 40225, Germany

  • Universitätsklinikum Düsseldorf, Institut für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Düsseldorf, 40225, Germany

  • Universitätsklinikum Erlangen, Allgemeinmedizinisches Institut

    RECRUITING

    Erlangen, 91054, Germany

  • Universitätsklinikum Erlangen, Radiologisches Institut

    RECRUITING

    Erlangen, 91054, Germany

  • Universitätsklinikum Gießen, Diagnostische und Interventionelle Radiologie und Kinderradiologie

    RECRUITING

    Giessen, 35392, Germany

  • Universitätsklinikum Hamburg-Eppendorf, Institut und Poliklinik für Allgemeinmedizin

    RECRUITING

    Hamburg, 20246, Germany

  • Universitätsklinikum Jena, Institut für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Jena, 07747, Germany

  • Universitätsklinikum Köln, Institut für Allgemeinmedizin

    RECRUITING

    Cologne, 50937, Germany

  • Universitätsklinikum Leipzig, Institut für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Leipzig, 04103, Germany

  • Universitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Radiologie und Neuroradiologie

    RECRUITING

    Kiel, 24105, Germany

  • Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Institut für Allgemeinmedizin

    RECRUITING

    Lübeck, 23538, Germany

  • Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Institut für Radiologie und Nuklearmedizin

    RECRUITING

    Lübeck, 23538, Germany

  • Universitätsklinikum Tübingen, Diagnostische und Interventionelle Radiologie, Department für Radiologie

    RECRUITING

    Tübingen, 72076, Germany

  • Universitätsklinikum Tübingen, Institut für Allgemeinmedizin & Interprofessionelle Versorgung

    RECRUITING

    Tübingen, 72076, Germany

  • Universitätsklinikum Ulm, Institut für Allgemeinmedizin

    RECRUITING

    Ulm, 89081, Germany

  • Universitätsklinikum Ulm, Klinik für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Ulm, 89081, Germany

  • Universitätsklinkum Würzburg, Institut für Diagnostische und Interventionelle Radiologie

    RECRUITING

    Würzburg, 97080, Germany

  • Universitätsmedizin Greifswald, Institut für Community Medicine, Abt. Allgemeinmedizin

    RECRUITING

    Greifswald, 17475, Germany

  • Universitätsmedizin Göttingen, Institut für Allgemeinmedizin

    RECRUITING

    Göttingen, 37073, Germany

  • Universitätsmedizin Rostock, Institut für Allgemeinmedizin

    RECRUITING

    Rostock, 18057, Germany

  • Universitätsmedizin Rostock, Institut für Diagnostische und Interventionelle Radiologie, Kinder- und Neuroradiologie

    RECRUITING

    Rostock, 18057, Germany

  • radiomed Gemeinschaftspraxis für Radiologie und Nuklearmedizin

    RECRUITING

    Wiesbaden, 65185, Germany

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