Pfizer

This study tests an experimental RSV vaccine in 130 adults aged 18 to 59 in Japan who have health conditions that raise their risk of severe RSV. The vaccine is designed to help the body build defenses against the virus. Researchers will monitor safety and immune response for abo…

This study tests a new vaccine (PG4) to see if it is as safe as the current pneumococcal vaccine (Prevnar 20) in healthy infants. About 2400 babies around 2 months old will receive either the new or current vaccine at 2, 4, 6, and 12-15 months of age. The goal is to protect again…

This early-phase study tests a new drug, PF-07994525, in 120 adults with advanced multiple myeloma that has returned or not responded to treatment. The goal is to find a safe dose and see if the drug can shrink tumors. Researchers will closely monitor side effects and how the bod…

This study looks at how safe and effective Zavicefta is for people with severe infections (sepsis) or kidney problems. About 59 patients in Japan will be followed for 28 days after their first dose. The goal is to track side effects and how well the drug works in real-world use.

This study tests a new experimental drug (PF-08634404) combined with chemotherapy against an approved drug (pembrolizumab) plus chemotherapy in adults with advanced or recurrent MMR-proficient endometrial cancer. About 600 women will be randomly assigned to one of two groups and …

This study tracks 600 people in Korea with advanced breast cancer and a BRCA gene mutation who are prescribed Talzenna by their doctor. Researchers will watch for side effects and measure how well the drug controls the cancer in real-life settings, not a lab. The goal is to confi…

This study tests a once-monthly injection called berobenatide to help adults with overweight or obesity lose weight. About 954 participants will receive either the drug or a placebo for 20 months. The goal is to see if the drug is safe and effective for weight loss, including in …

This study tests a new medicine, PF-08634404, given alone or with chemotherapy for adults with early or locally advanced non-small cell lung cancer. The goal is to see if it helps shrink tumors before surgery or prevents cancer from returning after treatment. About 120 participan…

This study tests two experimental drugs, PF-08653945 and PF-08653944, given alone or together, to help adults with overweight or obesity lose weight. About 872 participants will receive either the drugs or a placebo. The main goal is to see how much weight they lose and if the dr…

This study will monitor 3,000 adults in Korea who take NURTEC ODT 75 mg for migraines, either to stop an attack or prevent future ones. Researchers will track side effects and how well the drug works, like whether it makes pain go away within 2 hours. The goal is to confirm the d…

This study checks if a new version of a migraine drug works the same as the approved one. It involves 36 healthy adults who will take both forms and have their blood tested. The goal is to see if the new form is just as effective and safe, which could give patients more options.

This early-stage study looks at whether the antifungal drug itraconazole changes how the body processes an experimental medicine (PF-08642534) in healthy adults. About 14 participants aged 18-65 will receive single doses of the study drug with and without itraconazole. The study …

This study looks at how different liquid versions of the drug osivelotor taste and how well they get into the blood compared to a tablet. It also checks if taking the drug with food or an antacid changes absorption. About 52 healthy adults aged 18 to 65 will take part. The goal i…

This early-stage study in 24 healthy adults aims to understand how different versions of the experimental medicine PF-08049820 are absorbed and cleared from the body. Participants will take the medicine under various conditions—with or without food, and with or without a stomach-…

This study looks at the safety of a drug called Bevacizumab BS (a biosimilar to Avastin) in 1000 colorectal cancer patients in Japan. Researchers will check how often serious side effects like bleeding, high blood pressure, and kidney problems happen. The goal is to understand re…

This study will observe about 30 adults in Taiwan with relapsed or refractory multiple myeloma who are taking the drug elranatamab. Researchers want to see how well the drug works in everyday medical practice, not just in controlled trials. They will track things like how long it…

This study tracks the safety and effectiveness of TUKYSA in 600 adults with HER2-positive advanced or metastatic breast cancer in Korea. Participants will receive TUKYSA as part of their normal care, and researchers will monitor their response and any side effects. The goal is to…

This study tests if a new orally disintegrating tablet of tafamidis works the same as the current capsule in healthy adults. About 30 participants will take both forms under fasting conditions to compare drug levels in the blood. The goal is to see if the tablet can be a convenie…

This study looks at health records of babies born in Scotland to see if those whose mothers received the RSV vaccine (ABRYSVO) during pregnancy have fewer hospital visits for RSV. Researchers will compare vaccinated and unvaccinated groups using existing national data, without co…

This early-stage study tests a new medicine, PF-08065010, in 100 healthy adults aged 18-65 to check its safety and how the body processes it. Participants receive either the drug or a placebo as a shot or IV, with some getting a single dose and others monthly doses for 3 months. …

This early-stage study tests a new Pfizer medicine (PF-08057418) in 8 healthy adults to see if it is safe and how the body processes it. Participants receive the drug once a week for 5 weeks as a solution or tablet. The study is not yet recruiting and focuses on safety and drug l…

This study uses a tiny radioactive tag to follow a new medicine as it travels through the body. Nine healthy men will take the drug by mouth and later by IV to see how much enters the blood and how it leaves the body. The goal is to learn about the drug's behavior, not to treat a…

This study will look at medical records from 3,000 adults with advanced bladder cancer to see how long their first treatment keeps the disease from getting worse. Researchers will also track which medicines doctors actually prescribe. This is not a new treatment trial—it simply o…