Pfizer

This study is testing a 5th booster dose of the VLA15 Lyme disease vaccine. It aims to see if the extra dose is safe and helps maintain strong protection against Lyme disease. The study will include about 1,700 healthy people aged 7 and older who have already received 4 doses of …

This study will monitor the real-world safety and effectiveness of Talzenna, a drug already approved for treating advanced breast cancer with specific genetic mutations (gBRCA) in Korea. It will observe 600 patients who are prescribed Talzenna by their doctors as part of normal m…

This study aims to see how well the medication ritlecitinib works for people with severe alopecia areata (an autoimmune condition causing hair loss) in real-world medical settings. It will look back at the medical records of about 300 people in the U.S. who were prescribed this d…

This study is testing a new drug, PF-08634404, combined with standard chemotherapy for people with advanced stomach or esophageal cancer that has spread. The goal is to see if this combination is safe and works better than current standard treatments. It is for adults who have no…

This study is testing a new medicine called PF-08634404 to see if it can help adults with early-stage non-small cell lung cancer. The medicine will be given either alone or with chemotherapy, depending on whether the cancer can be removed with surgery. Researchers want to see if …

This study is testing a new medicine, PF-08634404, for adults with advanced bladder cancer that has spread. It will see if the drug is safe, how well it works to control the cancer, and how the body processes it. One group will get the new drug alone, and another group will get i…

This study is testing a daily oral medication called etrasimod in children aged 2 to 12 who have moderately to severely active ulcerative colitis, a chronic inflammatory bowel disease. The main goal is to see if the drug is safe, effective at controlling the disease, and how it b…

This study aims to monitor the safety and effectiveness of the breast cancer drug TUKYSA in real-world medical practice in Korea. It will enroll 600 adults with advanced HER2-positive breast cancer who are starting TUKYSA treatment as prescribed by their doctor. The main goal is …

This study will monitor the safety and effectiveness of Velsipity tablets over one year in patients with moderate to severe ulcerative colitis. Researchers will track 553 patients taking the medication in real-world medical settings to identify any long-term side effects. The mai…

This study is testing whether a new medicine called PF-08634404 works better when given with standard chemotherapy for a rare, aggressive form of lung cancer called transformed small cell lung cancer. The trial will enroll 40 adults who haven't received treatment for this specifi…

This study aims to monitor the safety and real-world effectiveness of the antibiotic Zavicefta in Japan. It will include about 59 patients who have severe bloodstream infections (sepsis) or reduced kidney function and are receiving Zavicefta for the first time. Researchers will t…

This is the first study in people for a new drug called PF-07994525, developed by Pfizer. It aims to find a safe dose and see if the drug shows early signs of fighting cancer in adults with advanced multiple myeloma that has stopped responding to other treatments. The study will …

This study aims to see how well the drug elranatamab works for patients in Taiwan with multiple myeloma that has come back or stopped responding to other treatments. It will follow about 30 adults who have already tried at least four other therapies. The goal is to understand how…

This early-stage study aims to understand how a new drug, PF-07328948, is absorbed, broken down, and removed from the body. It will involve a small group of healthy adult male volunteers. Researchers will track a tiny, safe amount of a radioactive version of the drug to see exact…

This study will analyze treatment patterns and outcomes for 4,000 people with ulcerative colitis using existing medical records. Researchers want to understand how patients respond to different medications over time and whether switching treatments earlier leads to better long-te…

This study looks back at existing German health insurance records to better understand ATTR-CM, a rare and serious heart condition. Researchers will analyze data from people diagnosed between 2020 and 2022 to learn about their survival rates, hospital visits, and how common the d…

This study aims to see if a new tablet form of the drug tafamidis gets into the bloodstream the same way as the currently available capsule. It will involve 24 healthy adult volunteers who will take both forms after eating a meal. The main goal is to check if the two forms are eq…

This study will use existing Scottish national health records to see if babies born to mothers who received the RSV vaccine (ABRYSVO) are less likely to be hospitalized with severe RSV infections in their first year of life. It will compare these infants to those whose mothers di…

This study examines how the body processes an experimental cancer medicine called vepdegestrant in people with liver problems compared to those with normal liver function. Researchers will give a single oral dose to 24 participants and measure how the medicine moves through their…

This study aims to understand how well current treatments work for advanced bladder cancer in everyday medical practice. Researchers will review existing health records of 3,000 U.S. patients who started treatment after April 2023. The study will track how long treatments keep th…

This is an early safety study to test a new medicine called PF-08065010, which is being developed for rheumatoid arthritis and lupus. The study will involve 100 healthy adults who will receive either the study medicine or a placebo injection or infusion. Researchers will monitor …