Orthocarolina Research Institute, Inc.
Clinical trials sponsored by Orthocarolina Research Institute, Inc., explained in plain language.
Upcoming readouts
Trials from this sponsor expected to report results within the next 12 months.
- New pain pumps aim to ease recovery after knee replacement Results expected Sep 2026 (estimated)
- Opioid-Free pain control for teens after scoliosis surgery: a safer way? Results expected Dec 2026 (estimated)
- Bone-Delivered antibiotics could spare joint infection patients from repeat surgeries Results expected Jan 2027 (estimated)
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Blood test may predict need for hip revision surgery
Diagnosis Stopped earlyThis study aimed to develop a biomarker test using blood or joint fluid to detect tissue damage (necrosis) caused by metal-on-metal hip implants. Researchers planned to enroll 174 patients, including those needing revision surgery and a control group. The goal was to see if the t…
Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 12:37 UTC
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Spine surgery pain study halted early: which method works best?
Symptom relief Stopped earlyThis study aimed to see if a combination of pain medicines (multimodal analgesia) works better than standard care for pain after lower back fusion surgery. It included 50 adults aged 18 to 70. The study was stopped early, so results are limited.
Phase 4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Knee replacement pain study seeks best relief combo
Symptom relief Stopped earlyThis study looked at whether adding a nerve block (adductor canal block) to a standard pain injection around the knee provides extra pain relief for people having total knee replacement. About 93 adults with osteoarthritis participated. The goal was to find the best way to manage…
Phase 2/3 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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ACL surgery study halted: did tourniquet use matter?
Knowledge-focused Stopped earlyThis study aimed to see if using a tourniquet less during ACL reconstruction surgery helps patients recover quadriceps muscle function faster and with less pain. Only 1 person was enrolled before the trial was terminated, so no meaningful results were obtained. The study was desi…
Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC