Orthocarolina Research Institute, Inc.

This study tests whether giving antibiotics directly into the bone during a standard cleaning procedure can better control joint infections after knee replacement. About 100 adults with an infected knee joint will receive this targeted antibiotic approach. The goal is to see if i…

This study tests a new approach called Targeted Brain Rehabilitation (TBR) to prevent phantom limb pain in people undergoing major amputation. Participants will use virtual reality daily while in the hospital after surgery. The goal is to see if this brain training can reduce or …

This study compares two types of pain pumps placed in the knee after total knee replacement surgery. 65 adults having knee replacement will be randomly assigned to receive standard pain care alone or standard care plus one of two pain pumps. The goal is to see which approach prov…

This study tests whether a pain management plan without opioids works as well as the usual opioid-containing plan for teenagers having scoliosis surgery. About 58 teens aged 10-20 will be enrolled. The goal is to see if the opioid-free approach can control pain just as well, whil…