Odense University Hospital

The RELEASE trial tests whether adults aged 65 and older with stable ischemic heart disease can safely stop their daily low-dose aspirin. Researchers will compare stopping aspirin against continuing it in 7,000 participants who have been free of heart events for at least two year…

This phase II trial is testing whether combining teclistamab, an antibody that helps immune cells attack myeloma cells, with pomalidomide, a drug that slows cancer growth, can control multiple myeloma in people whose disease has returned or stopped responding after 1-3 prior trea…

This study tests whether a single, powerful dose of MRI-guided radiation can safely treat prostate cancer that has come back in a few lymph nodes after initial treatment. Forty-eight men will receive one 24 Gy radiation session aimed precisely at the affected nodes. The main goal…

This trial tests whether measuring glucose in umbilical cord blood, already collected at birth, can screen newborns for congenital hyperinsulinism, a condition that causes dangerously low blood sugar and can lead to brain damage if missed. Researchers will check the test's accura…

This study tests a new type of PET/CT scan that targets a protein called FAP, which is found in many breast cancers. The goal is to see if this scan can find cancer spread more accurately than current scans, helping doctors plan better treatment. About 65 adults with newly diagno…

This trial tests whether taking dapagliflozin (Forxiga) for 12 months can prevent post-transplant diabetes in kidney transplant recipients who do not have diabetes. The study includes 184 adults who recently received a kidney transplant and are on standard immunosuppressive thera…

This study looks at whether people with multiple myeloma can safely give themselves the drug daratumumab at home instead of going to the hospital. About 50 patients will take turns receiving the injection at home and at the clinic to compare the two approaches. The goal is to see…

This phase 2 trial tests whether verteporfin, a drug injected into the skin during tummy tuck surgery, can reduce scar formation. Twelve adults will receive different doses of verteporfin and a placebo in separate parts of their surgical wound. Researchers will compare scar appea…

This study tests whether pulsatile compression boots, which rhythmically squeeze the legs, can help patients hospitalized with acute heart failure and leg swelling. The boots aim to move fluid out of the legs, improve circulation, and support heart and kidney function. One hundre…

This study looks at whether pregnant women at high risk of preterm birth can safely express breastmilk from week 28 to 34 of pregnancy. Researchers will check if it affects how soon the baby is born, how much milk is available at birth, and whether it helps with breastfeeding. Th…

Researchers at Odense University Hospital are testing whether monitoring brain signals during tumor surgery can help preserve functions like movement, speech, and vision. The project includes a randomized trial comparing surgery with and without motor signal monitoring, plus obse…

This study tests whether a blood test using mass spectrometry can detect minimal residual disease (tiny amounts of cancer left after treatment) in multiple myeloma patients. Currently, doctors must take bone marrow samples, which is painful and inconvenient. The blood test would …

This study tests a tool called HYSAT that rates how well doctors perform hysteroscopy, a procedure to look inside the uterus. Researchers will observe 24 doctors at three hospitals, comparing novices and experienced doctors. The goal is to see if the tool reliably measures skill,…

This study looks at why some people with blood cancers like multiple myeloma or lymphoma choose not to receive treatment at home, or are not eligible for it. Researchers will interview patients, their caregivers, and healthcare staff, and review medical records and questionnaires…

This study looks at whether a lighter ankle stirrup helps people recover physical activity faster than a standard rigid brace after an ankle fracture. About 280 adults with ankle fractures will wear activity trackers for 12 weeks to measure movement. The goal is to see if allowin…

This observational study looks at how having type 2 diabetes impacts quality of life in cancer patients receiving immunotherapy. Researchers will compare changes in well-being over six months between patients with and without diabetes. About 920 adults with solid tumors will fill…