Nationwide Children's Hospital

This study tests a new treatment for acute myeloid leukemia (AML) that has returned or not responded to standard therapy. It uses specially engineered immune cells from a healthy donor to target and kill cancer cells. The trial has two phases: first to find the safest dose, then …

This study tests a drug called tovorafenib in children and young adults (ages 1 to 39) newly diagnosed with aggressive brain tumors (high-grade glioma or DIPG) that have specific genetic changes. The goal is to see if the drug can help patients live longer by targeting those gene…

This study tests a new program where parents help their hospitalized infants with swallowing problems learn to eat by mouth. The goal is to see if the program helps babies avoid needing a long-term feeding tube. About 134 infants will take part, and researchers will track feeding…

This study looks at two standard treatments for a type of brain tumor called low-risk medulloblastoma in children under 5. The goal is to see which treatment better protects thinking and learning skills 2.5 years after diagnosis. About 96 children will take part, and researchers …

This study will test a device called TetraGraph to see exactly how quickly the muscle relaxant rocuronium takes effect and wears off in 130 people having surgery. Doctors usually wait 60 seconds after giving the drug, but it doesn't always work that fast, which can make intubatio…

This study will use a special brain imaging technique (fNIRS) to measure how virtual reality (VR) changes brain activity and reduces pain in children aged 6-17 who have burn injuries. Four children will have their brain signals recorded during burn dressing changes with and witho…