National Institute On Drug Abuse (nida)

This study looked at how things like neighborhood environment, social networks, and stress influence drug use, addiction, and whether people seek treatment. Over 1,600 adults from Baltimore took part, providing samples and answering questions over a year. The goal was to understa…

This study tested whether an experimental drug called SXC-2023 changes how the body reacts to cocaine. Nineteen adults who use cocaine but were not seeking treatment took part. Researchers measured safety, heart rate, and blood pressure after giving cocaine to those who had taken…

This study tested whether portable devices like PDAs and GPS units can give a more accurate, real-time picture of stress and drug use in people being treated for heroin addiction. 373 participants carried these devices for 16 weeks while on methadone treatment, recording drug use…

This study looked at how gut bacteria differ between people with alcohol use disorder who are currently drinking, those who are abstinent, and healthy moderate drinkers. Researchers collected stool samples and measured cravings in a bar-like setting. The goal was to understand if…

This study screened nearly 7,000 volunteers to find people eligible for future research on drug addiction and its effects on the brain and body. Participants completed phone and in-person interviews, medical exams, and lab tests. No treatment or clinical care was provided.

This study looked at how nicotine addiction changes brain activity and which genes might make quitting harder. Researchers used brain scans and genetic tests on 159 current and former smokers, as well as non-smokers. The goal was to find biological markers that could predict who …

This study looked at how genes influence addiction and thinking skills like memory and decision-making. Researchers collected blood samples and had 847 adults (healthy volunteers, smokers, and people with substance use or other psychiatric disorders) complete questionnaires and c…

This study tested new computer tasks to see how drugs affect brain activity using MRI scans. Healthy volunteers aged 18 to 65, both drug users and non-users, performed memory and reaction-time tests while in a scanner. The goal was to develop reliable tools for future research on…