National Institute On Aging (nia)

This study aimed to understand how the body's endocannabinoid system, which is involved in appetite and mood, affects insulin production and action. Researchers tested two experimental drugs (nabilone and CP-945,598) in 45 healthy male volunteers to see how they changed insulin l…

This study tested whether a ketone ester drink could change how the brain uses energy and improve thinking skills. It involved 99 adults aged 55 and older who had metabolic syndrome but normal memory. Participants drank either the ketone supplement or a placebo three times a day …

This study aimed to understand how aging cells behave during wound healing. Researchers took small skin samples from healthy young adults (20-39) and older adults (70+) after creating minor wounds. The goal was to see if older cells respond differently, which could help future re…

This study tested a new program where emergency room pharmacists review the medications of patients with dementia or mild memory problems. The goal was to see if pharmacists could identify and recommend stopping unnecessary or potentially harmful brain-affecting drugs, and then c…

This early study tested the safety of a new drug called BNC, which is being developed for Alzheimer's disease. Researchers gave single doses to 75 healthy volunteers aged 55 and older to see how their bodies processed the drug and to check for side effects. The study was designed…

This study aimed to understand why many older adults develop anemia (low red blood cells) without a clear cause. Researchers tracked how long red blood cells live in healthy younger adults, healthy older adults, and older adults with different types of anemia. They used a safe vi…

This study aimed to understand how two existing drugs—one for lung disease and one for diabetes—affect hormones that control blood sugar. Researchers tested the drugs on 29 healthy volunteers to see if they work together to boost helpful gut hormones. The goal was to gather basic…

This study aimed to understand if giving growth hormone to healthy men could improve how their immune system works. Researchers enrolled 66 healthy men aged 25-50 and gave some of them growth hormone infusions via a small pump under the skin for several weeks, while others receiv…